A6933
Acetyl-Amyloid β-Protein Fragment 15-20 Amide
≥97% (HPLC), powder
别名:
Ac-QKLVFF-NH2, amyloid blocker
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关于此项目
经验公式（希尔记法）:
C42H63N9O8
化学文摘社编号:
分子量:
822.01
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
Form:
powder
Assay:
≥97% (HPLC)
Quality Segment
assay
≥97% (HPLC)
form
powder
color
white
UniProt accession no.
storage temp.
−20°C
SMILES string
CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(C)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc2ccccc2)C(N)=O
InChI
1S/C42H63N9O8/c1-25(2)22-33(49-38(55)30(18-12-13-21-43)47-39(56)31(46-27(5)52)19-20-35(44)53)41(58)51-36(26(3)4)42(59)50-34(24-29-16-10-7-11-17-29)40(57)48-32(37(45)54)23-28-14-8-6-9-15-28/h6-11,14-17,25-26,30-34,36H,12-13,18-24,43H2,1-5H3,(H2,44,53)(H2,45,54)(H,46,52)(H,47,56)(H,48,57)(H,49,55)(H,50,59)(H,51,58)/t30-,31-,32-,33-,34-,36-/m0/s1
InChI key
DDXTVYDSGCHGAN-PITCCTKHSA-N
Gene Information
human ... APP(351)
Biochem/physiol Actions
Amyloid plaques characteristic of the Alzheimer brain contain fibrils composed of amyloid beta aggregates. Short peptides containing the sequence KLVFF have been shown to bind specifically to the homologous region in Aβ and are used to prevent full length amyloid fibril formation.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)