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Merck
CN

A7384

Sigma-Aldrich

Agaric acid

别名:

2-Hydroxy-1,2,3-nona­decane­tricarboxylic acid, Agaricic acid, Agaricin

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关于此项目

经验公式(希尔记法):
C22H40O7
化学文摘社编号:
分子量:
416.55
EC 号:
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:
NACRES:
NA.25
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表单

powder

SMILES字符串

CCCCCCCCCCCCCCCCC(C(O)=O)C(O)(CC(O)=O)C(O)=O

InChI

1S/C22H40O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18(20(25)26)22(29,21(27)28)17-19(23)24/h18,29H,2-17H2,1H3,(H,23,24)(H,25,26)(H,27,28)

InChI key

HZLCGUXUOFWCCN-UHFFFAOYSA-N

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应用

Agaric acid (Agaricic acid), an inducer of mitochondrial permeability transition (MPT), is used to study the MPT process at the level of the ADP and ATP exchange via the adenine nucleotide carrier/translocase.

其他说明

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Noemí García et al.
Cell biochemistry and biophysics, 51(2-3), 81-87 (2008-07-24)
In this work, we studied the effect of N-ethylmaleimide on permeability transition. The findings indicate that the amine inhibited the effects of carboxyatractyloside and agaric acid. It is known that these reagents interact with the adenine nucleotide carrier through the
L Wojtczak et al.
Journal of bioenergetics and biomembranes, 31(5), 447-455 (2000-02-01)
Nonesterified long-chain fatty acids have long been known as uncouplers of oxidative phosphorylation. They are efficient protonophores in the inner mitochondrial membrane but not so in artificial phospholipid membranes. In the un-ionized form, they undergo a rapid spontaneous transbilayer movement
J Kanaani et al.
The Journal of biological chemistry, 264(6), 3194-3199 (1989-02-25)
The metabolic inter-relationships between malarial parasites and their host erythrocytes are poorly understood. They have been investigated hitherto mostly by observing parasite behavior in erythrocyte variants, in metabolically altered erythrocytes, or in cell-free in vitro systems. We have studied the
Z X Xu et al.
Biochimica et biophysica acta, 1044(1), 70-76 (1990-05-01)
Fetal lung fatty-acid synthase and choline-phosphate cytidylyltransferase activities are increased by glucocorticoids. There is evidence that the hormone increases synthesis of fatty-acid synthase but only increases the catalytic activity of the cytidylyltransferase. Free fatty acids and a number of phospholipids
Agaric acid.
R A Freedland et al.
Methods in enzymology, 72, 497-506 (1981-01-01)

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