产品名称
Anti-c-Myc 琼脂糖亲和凝胶 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
agarose conjugate
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
analyte chemical class(es)
proteins (c-Myc)
technique(s)
affinity chromatography: suitable
immunoprecipitation (IP): suitable
capacity
≥10 nmol/mL binding capacity (c-Myc tagged fusion protein)
≥7 nmol/mL elution capacity (c-Myc tagged fusion protein)
UniProt accession no.
storage temp.
2-8°C
Quality Level
Gene Information
human ... MYC(4609)
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Application
兔源抗c-Myc琼脂糖亲和凝胶抗体已用于：
- 染色质免疫沉淀 (ChIP)
- 免疫共沉淀
- 蛋白质印迹
- 免疫荧光
- 免疫沉淀
Biochem/physiol Actions
抗c-Myc可识别位于c-Myc标记融合蛋白上的表位。
许多人类肿瘤中观察到c-Myc原癌基因表达增加。在血管肉瘤中观察到Myc基因位点扩增，在伯基特氏淋巴瘤中Myc基因位点出现易位。c-Myc是主要的调控基因，可靶向多种代谢事件。位于人c-Myc氨基酸残基410-419（EQKLISEEDL）内的表位已在许多表达载体中广泛用作标签，使蛋白质能够作为c-Myc标记融合蛋白进行表达。抗c-Myc琼脂糖可用于纯化细菌裂解液或转染细胞中表达的c-Myc标记融合蛋白。
Disclaimer
除非我们的产品目录另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
人c-Myc原癌基因属于MYC癌基因家族，是在几种致白血病逆转录病毒中发现的禽v-Myc基因的人细胞同源物。c-Myc基因位于人类染色体8q24.21。其两个主结构域包括具有螺旋-环-螺旋/亮氨酸-拉链基序的N末端盒区域和C末端基本区域
Immunogen
人p62c-Myc蛋白的合成肽。
Other Notes
Physical form
悬浮的琼脂糖颗粒(1：1，v/v)溶于0.01 M磷酸盐缓冲液中，含有15mM叠氮化钠。
Preparation Note
为持续使用并延长存储时间，请2°C至8°C存储。请勿冷冻。
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存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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