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安全信息

A7785

Sigma-Aldrich

Apolipoprotein C-I 来源于人类血浆

≥95% (SDS-PAGE), lyophilized powder

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CAS号:
2235444-72-9
MDL编号:
MFCD00162928
NACRES:
NA.77

生物来源

human

质量水平

200

检测方案

≥95% (SDS-PAGE)

形式

lyophilized powder

分子量

average mol wt 6.6 kDa

technique(s)

inhibition assay: suitable

UniProt登记号

P02654

储存温度

−20°C

Gene Information

human ... APOC1(341)

一般描述

Very low density lipoprotein.

应用

Apolipoprotein C-1 directly interferes with fatty acid uptake and is a major plasma inhibitor of cholesterol ester transfer protein. Apolipoprotein C-I has been used to develop a quantitative strategy, named secretome-derived isotopic tag (SDIT), to concurrently identify and quantify the adipocyte-secreted plasma proteins from normal and high-fat-diet (HFD) induced obese mice.

生化/生理作用

Interferes directly with fatty acid uptake and is the major plasma inhibitor of cholesterol ester transfer protein.

外形

Lyophilized from 10 mM NH4HCO3, pH 7.5

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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B S Suri et al.
The Biochemical journal, 178(2), 455-466 (1979-02-15)
1. The work reported was designed to provide quantitative information about the capacity of the extrahepatic tissues of the rat to degrade injected VLD lipoproteins (very-low-density lipoproteins, d less than 1.006) to LD lipoproteins (low-density lipoproteins, d 1.006--1.063) and to
Rong-Xia Li et al.
Journal of proteome research, 11(5), 2851-2862 (2012-03-13)
We developed a quantitative strategy, named secretome-derived isotopic tag (SDIT), to concurrently identify and quantify the adipocyte-secreted plasma proteins from normal and high-fat-diet (HFD) induced obese mice, based on the application of isotope-labeled secreted proteins from cultured mouse adipocytes as
Nathan L Meyers et al.
Biochemistry, 51(6), 1238-1248 (2012-01-24)
Apolipoprotein C-I (apoC-I) is an important constituent of high-density lipoprotein (HDL) and is involved in the accumulation of cholesterol ester in nascent HDL via inhibition of cholesterol ester transfer protein and potential activation of lecithin:cholesterol acyltransferase (LCAT). As the smallest

商品

Cholesterol Transport

Since cholesterol is a water-insoluble molecule it must be packaged for transport within the plasma. The particles that package cholesterol, cholesteryl esters, and triglycerides for transport, are called lipoproteins.

胆固醇的运输

由于胆固醇是水不溶性分子，必须包装后才能在血浆中运输。包装胆固醇、胆固醇酯和甘油三酯以便运输的颗粒称为脂蛋白。

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