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线性分子式:
C20H22N5O6SNa
化学文摘社编号:
分子量:
483.47
NACRES:
NA.85
PubChem Substance ID:
UNSPSC Code:
51282412
EC Number:
253-347-7
MDL number:
InChI key
UVOCNBWUHNCKJM-XFAPPKAWSA-M
InChI
1S/C20H23N5O6S.Na/c1-20(2)13(17(28)29)25-15(27)12(16(25)32-20)22-14(26)11(10-6-4-3-5-7-10)23-19(31)24-9-8-21-18(24)30;/h3-7,11-13,16H,8-9H2,1-2H3,(H,21,30)(H,22,26)(H,23,31)(H,28,29);/q;+1/p-1/t11-,12-,13+,16-;/m1./s1
SMILES string
[Na+].CC1(C)SC2[C@H](NC(=O)[C@H](NC(=O)N3CCNC3=O)c4ccccc4)C(=O)N2[C@H]1C([O-])=O
form
powder
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
mode of action
cell wall synthesis | interferes
storage temp.
room temp
Quality Level
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Application
Azlocillin is often used against <l>Pseudomonas aeruginosa </l>and has been used to develop novel antibiotic quantitation techniques .
Biochem/physiol Actions
Azlocillin is a semisynthetic penicillin and a β-lactam antibiotic. It acts by inhibition of penicillin-binding protein (PBP)-dependent bacterial cell wall synthesis.
General description
Chemical structure: ß-lactam
Other Notes
Keep container tightly closed in a dry and well-ventilated place.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
涉药品监管产品
此项目有
Venkata Raveendra Pothineni et al.
Scientific reports, 10(1), 3798-3798 (2020-03-04)
Lyme disease is one of most common vector-borne diseases, reporting more than 300,000 cases annually in the United States. Treating Lyme disease during its initial stages with traditional tetracycline antibiotics is effective. However, 10-20% of patients treated with antibiotic therapy
A Weber et al.
Antimicrobial agents and chemotherapy, 24(5), 750-753 (1983-11-01)
We describe a rapid, precise, and simple procedure for the quantitation of azlocillin in serum and in aqueous solutions by high-pressure, reverse-phase liquid chromatography. This method uses a single precipitation step, detection by dual-wavelength monitoring (220 and 254 nm), and
Structure-Activity Relationships of Different β-Lactam Antibiotics against a Soluble Form of Enterococcus faecium PBP5, a Type II Bacterial Transpeptidase.
Andrea M. Hujer, Malgosia Kania, et. Al
Journal of Affective Disorders, 49, 612-618 (2005)
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