产品名称
对氨基苯甲脒琼脂糖, (1:1 suspension in a 1.0 M NaCl + 20% ethanol solution)
biological source
plant
form
(1:1 suspension in a 1.0 M NaCl + 20% ethanol solution)
technique(s)
protein purification: suitable
matrix
cross-linked 6% beaded agarose
matrix activation
epichlorohydrin
matrix attachment
amino to carboxyl of spacer
matrix spacer
9 atoms
capacity
≥5 mg/mL binding capacity (trypsin)
storage temp.
2-8°C
Quality Level
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Application
p-Aminobenzamidine Agarose (pABA) can be used as an affinity ligand to bind and remove serine proteases in addition to Ca2+-binding proteins. It has also been used in medical applications as a tool for the purification of non-protease proteins.
Physical form
1:1 suspension in a 1.0 M NaCl + 20% ethanol solution
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Gulay Bayramoglu et al.
Bioprocess and biosystems engineering, 35(3), 423-431 (2011-08-20)
In this work, a new methodology is developed for selection of affinity ligands towards the enzyme "trypsin" using quartz crystals microbalance (QCM) technique. To achieve this goal, the surface amination of gold plated QCM crystals was achieved in 13.56 MHz
Massimo D'Agostino et al.
Nature, 551(7682), 634-638 (2017-11-02)
Membrane fusion in eukaryotic cells mediates the biogenesis of organelles, vesicular traffic between them, and exo- and endocytosis of important signalling molecules, such as hormones and neurotransmitters. Distinct tasks in intracellular membrane fusion have been assigned to conserved protein systems.
Paola Fortugno et al.
Journal of cell science, 115(Pt 3), 575-585 (2002-02-28)
Survivin is a member of the inhibitor of apoptosis gene family that has been implicated in both apoptosis inhibition and regulation of mitosis. However, the subcellular distribution of survivin has been controversial and variously described as a microtubule-associated protein or
Ya-Chi Su et al.
The Journal of biological chemistry, 286(36), 31904-31914 (2011-07-23)
To select residues in coagulation factor XIa (FXIa) potentially important for substrate and inhibitor interactions, we examined the crystal structure of the complex between the catalytic domain of FXIa and the Kunitz protease inhibitor (KPI) domain of a physiologically relevant
Tomas Erban
PloS one, 6(8), e22860-e22860 (2011-08-31)
p-aminobenzamidine (p-ABA) is used as a ligand in the purification of many serine proteases and in their removal from heterogeneous samples. Moreover, p-ABA has a potent ability to bind Ca(2+)-binding proteins. The binding ability and use of p-ABA in purification
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