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A8981

AS-252424

Name: AS-252424
Brand: SIGMA

≥98% (HPLC), solid

别名:

5-[[5-(4-Fluoro-2-hydroxyphenyl)-2-furanyl]methylene]-2,4-thiazolidinedione

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关于此项目

经验公式（希尔记法）:

C₁₄H₈FNO₄S

化学文摘社编号:

900515-16-4

分子量:

305.28

UNSPSC Code:

12352200

PubChem Substance ID:

329771025

MDL number:

MFCD11045281

Assay:

≥98% (HPLC)

Form:

solid

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属性

assay

≥98% (HPLC)

form

solid

color

yellow

solubility

DMSO: >20 mg/mL

storage temp.

2-8°C

SMILES string

Oc1cc(F)ccc1-c2ccc(\C=C3\SC(=O)NC3=O)o2

InChI

1S/C14H8FNO4S/c15-7-1-3-9(10(17)5-7)11-4-2-8(20-11)6-12-13(18)16-14(19)21-12/h1-6,17H,(H,16,18,19)/b12-6+

InChI key

OYYVWNDMOQPMGE-WUXMJOGZSA-N

说明

Biochem/physiol Actions

AS-252424 is a potent and selective phosphoinositide 3-kinase PI3Kγ inhibitor with IC₅₀ = 30 nM in a mouse model.

AS-252424 is a potent and selective phosphoinositide 3-kinase PI3Kγ inhibitor.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Phosphoinositide Kinases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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商品

Discover Bioactive Small Molecules for Kinase Phosphatase Biology

全球贸易项目编号

货号	GTIN
A8981-5MG	04061832433813
A8981-25MG	04061832433806