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Merck
CN

A9396

Sigma-Aldrich

腺苷-2′-磷酸

from yeast

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别名:
磷酸腺苷, 腺苷-2′-一磷酸, 2′-AMP, 2′-腺苷酸
经验公式(希尔记法):
C10H14N5O7P
CAS号:
分子量:
347.22
UNSPSC代码:
41106305
eCl@ss:
32160414
PubChem化学物质编号:
NACRES:
NA.51

生物来源

yeast

质量水平

检测方案

≥98% (HPLC)

形式

powder

溶解性

1 N NH4OH: 50 mg/mL, clear, colorless to faintly yellow

储存温度

−20°C

SMILES字符串

NC1=NC=NC2=C1N=CN2[C@H]3[C@H](OP(O)(O)=O)[C@H](O)[C@@H](CO)O3.[H]O[H].NC4=NC=NC5=C4N=CN5[C@H]6[C@H](OP(O)(O)=O)[C@H](O)[C@@H](CO)O6

InChI

1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(22-23(18,19)20)6(17)4(1-16)21-10/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

InChI key

QDFHPFSBQFLLSW-KQYNXXCUSA-N

相关类别

一般描述

腺苷-2′-一磷酸(2’-AMP)是一种腺嘌呤核苷酸,其中的单磷酸基团被酯化连接2′-位的糖基。

应用

2′-一磷酸腺苷(2′-AMP)是由 2′,3′-cAMP 水解产生的代谢产物。2′-AMP 通过 A2B 受体抑制肾小球前血管平滑肌细胞和肾小球系膜细胞的增殖。2′-AMP 用于猪 NADP 特异性异柠檬酸脱氢酶辅酶位点的新的光亲和标签的合成。2′,3′-cAMP 和 2′-AMP 代表了基于腺苷的细胞调节的一种新的未探索途径。

生化/生理作用

AMP是许多化合物的关键成分,这些化合物包括在能量代谢中起关键作用的辅酶A,以及某些关键氧化还原辅因子,如NAD+、NADP+和FAD。此外,AMP是RNA的关键成分,RNA是细胞中蛋白质合成和其它生物过程必不可少的物质。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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