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Merck
CN

A9481

AD 198

≥98% (HPLC), solid

别名:

N-Benzyladriamycin-14-valerate

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关于此项目

经验公式(希尔记法):
C39H43NO12
化学文摘社编号:
分子量:
717.76
UNSPSC Code:
12352200
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assay

≥98% (HPLC)

form

solid

color

red

solubility

DMSO: >10 mg/mL, H2O: insoluble

storage temp.

2-8°C

SMILES string

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NCc3ccccc3)[C@H](O)[C@H](C)O2)c4c(O)c5C(=O)c6c(OC)cccc6C(=O)c5c(O)c4C1

Biochem/physiol Actions

AD 198 is a PKC-delta activator. Phospholipid scramblase 3 (PLS3) is an enzyme that plays a critical role in mitochondrial morphology, functions, and apoptotic response. During apoptosis, activated protein kinase C-delta (PKC-delta) translocates to mitochondria and phosphorylates PLS3. Used to show that PLS3 is a critical downstream effector of PKC-delta in AD 198-induced apoptosis.
AD 198 is a PKC-delta activator.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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