生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
ascites fluid
抗体产品类型
primary antibodies
克隆
AT-B1, monoclonal
包含
15 mM sodium azide
技术
ELISA: 1:20,000 using aflatoxin B1-BSA
同位素/亚型
IgG1
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
一般描述
Monoclonal anti-Aflatoxin B (mouse IgG1 isotype) is 1 derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.Aflatoxins are a group of naturally occurring fungal toxins (mycotoxins) synthesized by Aspergillus flavus and Aspergillus parasiticus. It is found as contaminants in human and animal food such as corn, peanuts, tree nuts, cottonseed, cereal crops, beans, casssava, milo, sorghum, copra, rice, dried fish and beer.
Mycotoxins, a group of chemically diverse secondary fungal metabolites, induce a variety of toxic responses in humans and animals when food and feed containing these compounds are ingested. Rapidly quantitating levels of mycotoxin contamination can help reduce exposure to these toxins.
免疫原
aflatoxin B -KLH conjugate
应用
Monoclonal Anti-Aflatoxin B1 (G1, Q1, B2, G2) antibody produced in mouse has been used in indirect enzyme linked immunosorbent assay (ELISA) and fluorescence polarization assay.
生化/生理作用
Aflatoxin B (AFB) and its metabolites is known to act as potent carcinogens, mutagens and teratogens, in addition to its toxicity. Aflatoxins have been implicated in human hepatocellular carcinoma, outbreaks of aflatoxicosis, Rey′s syndrome, chronic hepatitis and increased mortality from infection in animal husbandry.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Physicochemical and immunological characterization of chitosan-coated bacteriophage nanoparticles for in vivo mycotoxin modeling
de Andrade CYT, et al.
Carbohydrate Polymers, 185, 63-72 (2018)
Robert J Lee et al.
Scientific reports, 6, 33221-33221 (2016-09-15)
Aflatoxins are mycotoxins secreted by Aspergillus flavus, which can colonize the respiratory tract and cause fungal rhinosinusitis or bronchopulmonary aspergillosis. A. flavus is the second leading cause of invasive aspergillosis worldwide. Because many respiratory pathogens secrete toxins to impair mucociliary
Development of a fluorescence polarization assay for the determination of aflatoxins in grains
Nasir MS and Jolley ME
Journal of Agricultural and Food Chemistry, 50(11), 3116-3121 (2002)
Screening of Lactobacillus casei strains for their ability to bind aflatoxin B1
Hernandez MA, et al.
Food And Chemical Toxicology, 47(6), 1064-1068 (2009)
Frances A Draughon et al.
Journal of food protection, 45(8), 703-706 (1982-06-01)
Aflatoxin B1 was mixed with eleven concentrations of sodium hydroxide, sodium hypochlorite and ammonium hydroxide. Aflatoxin was quantitated by fluorometric determination and toxicity of aflatoxin treated with NaOH and NH4OH was evaluated by the brine shrimp assay. Detoxified aflatoxin B1
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