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Merck
CN

A9847

血管生成素-2 人

>97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

别名:

Ang-2

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关于此项目

UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
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产品名称

血管生成素-2 人, >97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

biological source

human

recombinant

expressed in NSO cells

assay

>97% (SDS-PAGE)

form

lyophilized powder

mol wt

66 kDa by SDS-PAGE (reducing and non-reducing conditions)
66 kDa by SDS-PAGE

packaging

pkg of 25 μg

storage condition

avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)

impurities

endotoxin, tested

UniProt accession no.

storage temp.

−20°C

Quality Level

Gene Information

human ... ANGPT2(285)

Analysis Note

通过竞争结合测定法测量生物活性。

Biochem/physiol Actions

该配体在体内体外都是血管生成素-1 和 Tie-2 的天然抑制剂,在胚胎发育血管生成和维持成年脉管系统完整性方面具有重要作用。

Physical form

0.2 μm滤液冻干,溶液含20 mM MOPS、500 mM NaCl、0.1% PEG-8000、0.2% CHAPS,pH 7.0,每1 μg细胞因子含50 μg牛血清白蛋白。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Long non-coding RNA KCND1 protects hearts from hypertrophy by targeting YBX1.
Yang, et al.
Cell Death & Disease, 14, 344-344 (2023)
B Witzenbichler et al.
The Journal of biological chemistry, 273(29), 18514-18521 (1998-07-11)
Angiopoietin-1 and its putative natural antagonist, angiopoietin-2, were recently isolated, and the critical role of angiopoietin-1 in embryogenic angiogenesis was demonstrated by targeted gene disruption. Specific biological effects of angiopoietin-1, however, have yet to be defined. In this study we
Hsiu-Mei Chen et al.
Oncotarget, 6(17), 14940-14952 (2015-04-25)
Foretinib, a multiple kinase inhibitor undergoing clinical trials, could suppress the activity of hepatocyte growth factor (HGF) receptor c-MET and vascular endothelial growth factor receptor-2 (VEGFR-2). In addition, Foretinib may inhibit two critical lymphangiogenic signaling receptors VEGFR-3 and TIE-2. However

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