跳转至内容
Merck
CN

主要文件

查看所有文档

A9968

N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide

≥95%

别名:

Ac-IETD-pNA

登录 查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:
C27H38N6O12
分子量:
638.62
NACRES:
NA.32
PubChem Substance ID:
329771065
UNSPSC Code:
12352209
MDL number:
MFCD01318840
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

Quality Level

200

assay

≥95%

form

powder

storage temp.

−20°C

SMILES string

CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc(cc1)[N+]([O-])=O

InChI

1S/C27H38N6O12/c1-5-13(2)22(28-15(4)35)26(42)30-18(10-11-20(36)37)24(40)32-23(14(3)34)27(43)31-19(12-21(38)39)25(41)29-16-6-8-17(9-7-16)33(44)45/h6-9,13-14,18-19,22-23,34H,5,10-12H2,1-4H3,(H,28,35)(H,29,41)(H,30,42)(H,31,43)(H,32,40)(H,36,37)(H,38,39)/t13-,14+,18-,19-,22-,23-/m0/s1

InChI key

FHURKTIGZAIQGR-BQCLNCLCSA-N

Gene Information

human ... CARD8(22900), CASP8(841), CASP8AP2(9994), CFLAR(8837), GZMB(3002)
mouse ... CFLAR(117279), GZMB(171528)
rat ... CASP8(12370), CFLAR(12633), GZMB(14939), RGD1561819(502004), RGD1562700(502007)

Application

Chromogenic substrate for caspase 8 and granzyme B.

Biochem/physiol Actions

IETD is the sequence of amino acid residues 172-175 of procaspase 3, which is cleaved during apoptosis to produce the p12 subunit and a p20 peptide that is further cleaved to form the p17 subunit of mature caspase 3.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLCJ4582
SLCC5257
SLCB8407
SLBN9634V
021M1516V

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Qing Xie et al.
Oncology reports, 41(5), 2647-2656 (2019-03-14)
The aim of the present study was to investigate the potential anticancer effects of microRNA-216a on the growth of human breast cancer and the possible underlying mechanisms. The results demonstrated that serum microRNA-216a was significantly decreased in patients with breast
Zhensong Yue et al.
Oncology letters, 14(6), 7941-7946 (2018-01-19)
Sophoridine is an alkaloid extracted from
Xiaosheng Qu et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 180, 31-39 (2015-11-06)
The present work investigated the in vitro cytotoxicity of nematocyst venom (NV) from Chrysaora helvola Brandt (C. helvola) jellyfish against human MCF-7 and CNE-2 tumor cell lines. Potent cytotoxicity was quantified using the MTT assay (LC50=12.07±3.13 and 1.6±0.22μg/mL (n=4), respectively).
查看所有相关文献

全球贸易项目编号

货号GTIN
A9968-5MG04061833267684