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Merck
CN

AMAB90558

Monoclonal Anti-ANXA1 antibody produced in mouse

Prestige Antibodies® Powered by Atlas Antibodies, clone CL0199, purified immunoglobulin, buffered aqueous glycerol solution

别名:

ANX1, LPC1

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
Human Protein Atlas Number:
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产品名称

Monoclonal Anti-ANXA1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0199, purified immunoglobulin, buffered aqueous glycerol solution

shipped in

dry ice

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

CL0199, monoclonal

product line

Prestige Antibodies® Powered by Atlas Antibodies

form

buffered aqueous glycerol solution

species reactivity

human

enhanced validation

RNAi knockdown
Learn more about Antibody Enhanced Validation

Quality Level

Gene Information

human ... ANXA1(301)

concentration

1 mg/mL

UniProt accession no.

storage temp.

−20°C

target post-translational modification

unmodified

technique(s)

immunoblotting: 1 μg/mL
immunofluorescence: 2-10 μg/mL (Fixation/Permeabilization: PFA/Triton X-100)
immunohistochemistry: 1:500- 1:1000

pH range

7.2-7.4

isotype

IgG1

epitope sequence

PQLRRVFQKY

Application

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. We also provide Prestige Antibodies® protocols and other useful information.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:
  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.

Legal Information

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

Immunogen

Recombinant protein corresponding to annexin A1

Preparation Note

Upon arrival, mix gently and aliquot to avoid repeated freeze-thaw cycles

Physical form

100UL pack size is provided in a solution, in PBS(phosphate-buffered saline), pH 7.2, containing 40% glycerol and 0.02% sodium azide.

Large pack size of 1ml (at 1mg/ml) is available in PBS only, purified, biocide free, carrier free and glycerol free. Order here-Request a Bulk Order /services/support/bulk-quotation-request

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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Peng Chen et al.
Oncology letters, 21(2), 141-141 (2021-02-09)
Small cell lung cancer (SCLC) is a subtype of lung cancer with a poor prognosis, with bone metastasis being one of the main causes of treatment failure. Therefore, investigating new biomarkers associated with bone metastasis may result in positive treatment
Kevin L Allen et al.
PloS one, 15(6), e0234268-e0234268 (2020-06-05)
Annexin A1 (anxA1) is an immunomodulatory protein that has been proposed as a tumor vascular target for antitumor biologic agents, yet to date the vascular expression of anxA1 in specific tumor indications has not been systematically assessed. Attempts to evaluate

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