AV32069
Anti-PBX2 (AB2) antibody produced in rabbit
affinity isolated antibody
别名:
Anti-G17, Anti-HOX12, Anti-PBX2MHC, Anti-Pre-B-cell leukemia homeobox 2
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
46 kDa
种属反应性
human, guinea pig, horse, mouse, rat
浓度
0.5 mg - 1 mg/mL
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... PBX2(5089)
一般描述
PBX2 is a homeobox transcription factor that shares homology with the human proto-oncogene, PBX1. Studies have reported that PBX2 forms triple complexes with HOXA9 and MEIS1 in myeloid cells.
Rabbit Anti-PBX2 (AB2) antibody recognizes pig, human, mouse, and rat PBX2.
Rabbit Anti-PBX2 (AB2) antibody recognizes pig, human, mouse, and rat PBX2.
免疫原
Synthetic peptide directed towards the N terminal region of human PBX2
应用
Rabbit Anti-PBX2 (AB2) antibody can be used for western blot applications at a concentration of 0.5μg/ml.
生化/生理作用
PBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family. PBX2 gene was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. PBX2 is a transcriptional activator which binds to the TLX1 promoter. This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
其他说明
Synthetic peptide located within the following region: MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGK
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
W F Shen et al.
Molecular and cellular biology, 19(4), 3051-3061 (1999-03-19)
Aberrant activation of the HOX, MEIS, and PBX homeodomain protein families is associated with leukemias, and retrovirally driven coexpression of HOXA9 and MEIS1 is sufficient to induce myeloid leukemia in mice. Previous studies have demonstrated that HOX-9 and HOX-10 paralog
K Monica et al.
Molecular and cellular biology, 11(12), 6149-6157 (1991-12-01)
Two new homeobox genes, PBX2 and PBX3, were isolated on the basis of their extensive homology to PBX1, a novel human homeobox gene involved in t(1;19) translocation in acute pre-B-cell leukemias. The predicted Pbx2 and Pbx3 proteins are 92 and
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