Anti-TLE3 antibody produced in rabbit

TLE3 is known to function as a transcriptional coregulator of adipogenesis. It interacts with HESX1 and PROP1 to regulate transcriptional expression.
Rabbit Anti-TLE3 antibody recognizes human, zebrafish, rat, mouse, and canine TLE3.

Synthetic peptide directed towards the N terminal region of human TLE3

Rabbit Anti-TLE3 antibody can be used for western blot applications at a concentration of 2.5μg/ml.

The TLE genes are differentially expressed and encode nuclear proteins, consistent with the presence of sequence motifs associated with nuclear functions. These genes are the human homologues of Drosophila groucho, a member of the Notch signaling pathway which controls a number of different cell-fate choices in invertebrates and vertebrates.

Synthetic peptide located within the following region: GSSSGLLALGALGSQAHLTVKDEKNHHELDHRERESSANNSVSPSESLRA

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

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