Anti-BRD2 (AB1) antibody produced in rabbit

BRD2 encodes a transcription factor that is a bromodomain containing protein. Brd2/RING3 is known to associate with the chromatin binding domain of LANA-1 in KSHV (Kaposi′s sarcoma-associated herpesvirus)-infected cells. BRD2 may also be a susceptibility gene for juvenile myoclonic epilepsy.
Rabbit Anti-BRD2 (AB2) antibody recognizes human, mouse, rat, canine, zebrafish, chicken, bovine, and pig BRD2.

Synthetic peptide directed towards the middle region of human BRD2

Rabbit Anti-BRD2 is suitable for western blot applications at a concentration of 0.5 μg/ml.

BRD2 encodes a mitogen-activated kinase which localizes to the nucleus. BRD2 maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3 but sequence comparison suggests that the protein is not involved in the immune response. Homology to the Drosophila gene female sterile homeotic suggests that this human gene may be part of a signal transduction pathway involved in growth control.

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Synthetic peptide located within the following region: QEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDD

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