Anti-RBPJL antibody produced in rabbit

RBPJL (SUHL or RBPSUHL) is the human homolog of Drosophila Suppressor of Hairless. Mouse Rbpj functions as a transcription factor and modulates the Notch signaling pathway to maintain neural progenitors. It complexes with Ptf1a to regulate the specification of GABAergic neurons in mouse neural tubes.
Rabbit Anti-RBPJL antibody recognizes bovine, human, mouse, and rat RBPJL.

Synthetic peptide directed towards the N terminal region of human RBPJL

Rabbit Anti-RBPJL can be used for western blot applications at a concentration of 2.5 μg/ml.

In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). RBPSUHL is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). The protein encoded by this gene is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Synthetic peptide located within the following region: AHQAGETGPTVCGYMGLDSASGSATETQKLNFEQQPDSREFGCAKTLYIS

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