生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
IgG fraction of antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
94 kDa
种属反应性
dog, human, bovine, pig, mouse, rat
浓度
0.5 mg - 1 mg/mL
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... ZA20D1(56957)
一般描述
OTU deubiquitinase 7B (OTUD7B or CEZANNE or ZA20D1) is a de-ubiquitinating enzyme that is known to affect actin structure. It has been implicated in the invasion of squamous cell carcinoma (SCC).
Rabbit Anti-ZA20D1 antibody recognizes human, mouse, rat, canine, and bovine ZA20D1.
Rabbit Anti-ZA20D1 antibody recognizes human, mouse, rat, canine, and bovine ZA20D1.
免疫原
Synthetic peptide directed towards the middle region of human ZA20D1
应用
Rabbit Anti-ZA20D1 antibody can be used for western blot applications at a concentration of 1.25 μg/ml.
生化/生理作用
The ZA20D1 gene encodes an enzyme that cleaves ubiquitin from proteins. This gene has the ability to down-regulate NF-kappa B which plays a pivotal role in inflammatory processes through induction of adhesion molecules and chemokines.
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
其他说明
Synthetic peptide located within the following region: WKGGKEEAAGDGPVSEKPPAESVGNGGSKYSQEVMQSLSILRTAMQGEGK
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
S I Chaudhry et al.
Oncogene, 32(6), 747-758 (2012-03-28)
The invasion of squamous cell carcinoma (SCC) is a significant cause of morbidity and mortality. Here, we identify an E3 ligase, Traf6 and a de-ubiquitinating enzyme, Cezanne/ZA20D1, as important regulators of this process in organotypic models. Traf6 can promote the
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