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Merck
CN

AV34593

Sigma-Aldrich

Anti-ZA20D1 antibody produced in rabbit

IgG fraction of antiserum

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UNSPSC代码:
12352203
NACRES:
NA.41
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生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

IgG fraction of antiserum

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

94 kDa

种属反应性

dog, human, bovine, pig, mouse, rat

浓度

0.5 mg - 1 mg/mL

技术

western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

基因信息

human ... ZA20D1(56957)

一般描述

OTU deubiquitinase 7B (OTUD7B or CEZANNE or ZA20D1) is a de-ubiquitinating enzyme that is known to affect actin structure. It has been implicated in the invasion of squamous cell carcinoma (SCC).
Rabbit Anti-ZA20D1 antibody recognizes human, mouse, rat, canine, and bovine ZA20D1.

免疫原

Synthetic peptide directed towards the middle region of human ZA20D1

应用

Rabbit Anti-ZA20D1 antibody can be used for western blot applications at a concentration of 1.25 μg/ml.

生化/生理作用

The ZA20D1 gene encodes an enzyme that cleaves ubiquitin from proteins. This gene has the ability to down-regulate NF-kappa B which plays a pivotal role in inflammatory processes through induction of adhesion molecules and chemokines.

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

其他说明

Synthetic peptide located within the following region: WKGGKEEAAGDGPVSEKPPAESVGNGGSKYSQEVMQSLSILRTAMQGEGK

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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S I Chaudhry et al.
Oncogene, 32(6), 747-758 (2012-03-28)
The invasion of squamous cell carcinoma (SCC) is a significant cause of morbidity and mortality. Here, we identify an E3 ligase, Traf6 and a de-ubiquitinating enzyme, Cezanne/ZA20D1, as important regulators of this process in organotypic models. Traf6 can promote the

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