AV40487
Anti-EIF4G3 antibody produced in rabbit
affinity isolated antibody
别名:
Anti-Eukaryotic translation initiation factor 4 γ, 3
登录 查看组织和合同定价。
选择尺寸
关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
1
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
57 kDa
species reactivity
human
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... EIF4G3(8672)
General description
Eukaryotic translation initiation factor 4 gamma 3 (EIF4G3) is involved in protein translation within the mammalian mRNA ribosome complex. EIF4G3 has been shown to be a target of cytotoxic T lymphocyte (CTL) produced granzyme B (GrB) suggesting that EIF4G3 may be targeted by CTL cells as a mechanism to inhibit the use of host translational machinery by infectious viruses.
Immunogen
Synthetic peptide directed towards the N terminal region of human EIF4G3
Application
Anti-EIF4G3 polyclonal antibody is used to tag eukaryotic translation initiation factor 4 gamma 3 proteins for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the role of eukaryotic translation initiation factor 4 gamma 3 in the initiation of mRNA translation and as a target of CTL cells during infectious virus assault.
Biochem/physiol Actions
Anti-EIF4G3 polyclonal antibody reacts with human, mouse, rat, and bovine eukaryotic translation initiation factor 4 gamma 3 proteins.
EIF4G3 is probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5′-terminal secondary structure and recruitment of mRNA to the ribosome. It is thought to be a functional homolog of EIF4G1.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: TAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIA
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Xu Huang et al.
Journal of oncology, 2021, 4936207-4936207 (2021-07-02)
As a selective histone deacetylase (HDAC) inhibitor developed in China, chidamide has been applied for the treatment of refractory peripheral T-cell lymphoma (PTCL) and multiple solid tumors, including lung cancer. However, the underlying mechanisms are not well elucidated. In our
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持