AV44108
Anti-SLC15A4 antibody produced in rabbit
affinity isolated antibody
别名:
Anti-PHT1, Anti-FP12591, Anti-PTR4, Anti-Solute carrier family 15, member 4
产品名称
Anti-SLC15A4 antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
62 kDa
species reactivity
human
concentration
0.5 mg - 1 mg/mL
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SLC15A4(121260)
Application
Anti-SLC15A4 antibody produced in rabbit is suitable for western blotting at a concentration of 0.25μg/ml and for immunohistochemistry of paraffin-embedded tissue sections at a concentration of 4-8μg/ml.
Biochem/physiol Actions
SLC15A4 (PHT1; PTR4) is a peptide/histidine transporter expressed in the brain and the retina. This protein enables plasmacytoid dendritic cells to sense toll-like receptor ligands that aid in triggering immune responses to persistent viral infections. The expression of SLC15A4 has been implicated in the pathogenesis of lupus.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
Synthetic peptide directed towards the N terminal region of human SLC15A4
Other Notes
Synthetic peptide located within the following region: MEGSGGGAGERAPLLGARRAAAAAAAAGAFAGRRAACGAVLLTELLERAA
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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wgk
WGK 3
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Roberto Baccala et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(8), 2940-2945 (2013-02-06)
In vitro evidence suggests that plasmacytoid dendritic cells (pDCs) are intimately involved in the pathogenesis of lupus. However, it remains to be determined whether these cells are required in vivo for disease development, and whether their contribution is restricted to
T Yamashita et al.
The Journal of biological chemistry, 272(15), 10205-10211 (1997-04-11)
Here we report the cloning and functional characterization of a rat novel peptide/histidine transporter (PHT1), which was expressed in the brain and the retina. The cDNA encodes the predicted protein of 572 amino acid residues with 12 putative membrane-spanning domains.
Amanda L Blasius et al.
PLoS pathogens, 8(9), e1002915-e1002915 (2012-10-03)
Plasmacytoid dendritic cells (pDCs) are the major producers of type I IFN in response to viral infection and have been shown to direct both innate and adaptive immune responses in vitro. However, in vivo evidence for their role in viral
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