AV45043
Anti-ACVR2B antibody produced in rabbit
affinity isolated antibody
别名:
Acvr2B Antibody, Acvr2B Antibody - Anti-ACVR2B antibody produced in rabbit, Anti-Activin A receptor, type IIB
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关于此项目
NACRES:
NA.43
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
5
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
33 kDa
species reactivity
dog, guinea pig, human, horse, sheep, bovine, rat
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ACVR2B(93)
Immunogen
Synthetic peptide directed towards the C terminal region of human ACVR2B
Application
Anti-ACVR2B antibody produced in rabbit is suitable for western blotting at a concentration of 0.25μg/ml.
Biochem/physiol Actions
Activin A receptor, type IIB (ACVR2B) binds activin ligands that promote growth and differentiation via the TGF-β signaling. ACVR2B is expressed in adult hypothalamus and forebrain. Activin receptors IIA and IIB may regulate germ cell proliferation in the human ovary during primordial follicle formation and in mouse testis.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: HDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Sirisha H S Mendis et al.
Biology of reproduction, 84(2), 379-391 (2010-10-12)
Activin affects many aspects of cellular development, including those essential for reproductive fitness. This study examined the contribution of activin A to murine fetal testicular development, revealing contrasting outcomes of activin actions on Sertoli cells and gonocytes. Shortly after sex
M C Miller et al.
Journal of neuroendocrinology, 24(6), 962-972 (2012-02-03)
The inhibin/activin family of proteins is known to have a broad distribution of synthesis and expression in many species, as well as a variety of functions in reproductive and other physiological systems. Yet, our knowledge regarding the production and function
Se-Jin Lee et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(50), 18117-18122 (2005-12-07)
Myostatin is a secreted protein that normally functions as a negative regulator of muscle growth. Agents capable of blocking the myostatin signaling pathway could have important applications for treating human muscle degenerative diseases as well as for enhancing livestock production.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| AV45043-100UL | 04061836213725 |
| AV45043-50UG | 04061832071800 |