AV45055
Anti-AOC2 antibody produced in rabbit
affinity isolated antibody
别名:
Anti-Amine oxidase, copper containing 2 (retina-specific), Anti-DAO2, Anti-RAO
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
2
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
84 kDa
species reactivity
dog, bovine, mouse, human, rabbit, horse
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Quality Level
Gene Information
human ... AOC2(314)
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Immunogen
Synthetic peptide directed towards the middle region of human AOC2
Application
Anti-AOC2 antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.
Biochem/physiol Actions
Amine oxidase, copper containing 2 (retina-specific) belongs to the copper amine oxidases family that converts amines to aldehydes and ammonia in the presence of copper and quinone as cofactors. AOC2 degrades dopamine, histamine and putrescine and modulates the signal transmission in the retina. The AOC2 gene mutations may cause hereditary ocular diseases.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: QATMVDIHILVGKGAVQLLPGAVCVFEEAQGLPLRRHHNYLQNHFYGGLA
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Sam Kaitaniemi et al.
Cellular and molecular life sciences : CMLS, 66(16), 2743-2757 (2009-07-10)
Semicarbazide-sensitive amine oxidases (SSAOs) catalyze oxidative deamination of primary amines, but the true physiological function of these enzymes is still poorly understood. Here, we have studied the functional and structural characteristics of a human cell-surface SSAO, AOC2, which is homologous
Qiang Zhang et al.
Gene, 318, 45-53 (2003-10-31)
We have previously cloned a human, retina-specific, amine oxidase gene (RAO, gene symbol: AOC2), a member of the copper-binding amine oxidase super family. AOC2 shares sequence identity with the human kidney amine oxidase gene (KAO, gene symbol: AOC1) and the
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