AV45381
Anti-PTPRN antibody produced in rabbit
affinity isolated antibody
别名:
Anti-FLJ16131, Anti-IA-2, Anti-IA-2/PTP, Anti-IA2, Anti-ICA512, Anti-Protein tyrosine phosphatase, receptor type, N, Anti-R-PTP-N
产品名称
Anti-PTPRN antibody produced in rabbit, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
96 kDa
species reactivity
mouse, dog, rabbit, human, rat
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... PTPRN(5798)
Application
Anti-PTPRA (AB1) antibody produced in rabbit is suitable for western blotting at a concentration of 0.0625μg/ml.
Biochem/physiol Actions
Protein tyrosine phosphatase, receptor type N (PTPRN) is a member of protein tyrosine phosphatase (PTP) family involved in cell growth, differentiation and mitosis. PTPRN acts as an autoantigen in the sera of insulin-dependent diabetes mellitus patients and is the target of autoimmunity.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
Synthetic peptide directed towards the middle region of human PTPRN
Other Notes
Synthetic peptide located within the following region: EVQQVPSPVSSEPPKAARPPVTPVLLEKKSPLGQSQPTVAGQPSARPAAE
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
E Bonifacio et al.
Diabetes, 50(11), 2451-2458 (2001-10-27)
Several self-antigens have been reported as targets of the autoimmune response in nonobese diabetic (NOD) mice. The aim of this workshop was to identify autoantibody assays that could provide useful markers of autoimmunity in this animal model for type 1
Huichun Liang et al.
Oncogene, 37(15), 1961-1975 (2018-01-26)
It is well documented that hypoxia activates the hypoxia-inducible factor 1-alpha (HIF1α)/vascular endothelial growth factor A (VEGFA) axis to promote angiogenesis in breast cancer. However, it is unclear how this axis is negatively regulated. In this study, we demonstrated that
Tony Tiganis et al.
The Biochemical journal, 402(1), 1-15 (2007-01-24)
It is now well established that the members of the PTP (protein tyrosine phosphatase) superfamily play critical roles in fundamental biological processes. Although there has been much progress in defining the function of PTPs, the task of identifying substrates for
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