AV45381
Anti-PTPRN antibody produced in rabbit
affinity isolated antibody
别名:
Anti-FLJ16131, Anti-IA-2, Anti-IA-2/PTP, Anti-IA2, Anti-ICA512, Anti-Protein tyrosine phosphatase, receptor type, N, Anti-R-PTP-N
生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
96 kDa
种属反应性
mouse, dog, rabbit, human, rat
浓度
0.5 mg - 1 mg/mL
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... PTPRN(5798)
免疫原
Synthetic peptide directed towards the middle region of human PTPRN
应用
Anti-PTPRA (AB1) antibody produced in rabbit is suitable for western blotting at a concentration of 0.0625μg/ml.
生化/生理作用
Protein tyrosine phosphatase, receptor type N (PTPRN) is a member of protein tyrosine phosphatase (PTP) family involved in cell growth, differentiation and mitosis. PTPRN acts as an autoantigen in the sera of insulin-dependent diabetes mellitus patients and is the target of autoimmunity.
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
其他说明
Synthetic peptide located within the following region: EVQQVPSPVSSEPPKAARPPVTPVLLEKKSPLGQSQPTVAGQPSARPAAE
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
此项目有
E Bonifacio et al.
Diabetes, 50(11), 2451-2458 (2001-10-27)
Several self-antigens have been reported as targets of the autoimmune response in nonobese diabetic (NOD) mice. The aim of this workshop was to identify autoantibody assays that could provide useful markers of autoimmunity in this animal model for type 1
Huichun Liang et al.
Oncogene, 37(15), 1961-1975 (2018-01-26)
It is well documented that hypoxia activates the hypoxia-inducible factor 1-alpha (HIF1α)/vascular endothelial growth factor A (VEGFA) axis to promote angiogenesis in breast cancer. However, it is unclear how this axis is negatively regulated. In this study, we demonstrated that
Tony Tiganis et al.
The Biochemical journal, 402(1), 1-15 (2007-01-24)
It is now well established that the members of the PTP (protein tyrosine phosphatase) superfamily play critical roles in fundamental biological processes. Although there has been much progress in defining the function of PTPs, the task of identifying substrates for
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