Anti-ANP32E antibody produced in rabbit

Synthetic peptide directed towards the middle region of human ANP32E

Anti-ANP32E antibody produced in rabbit is suitable for western blotting at a concentration of 0.25μg/ml. It is also useful for immunohistochemistry at a concentration of 4-8μg/ml.

ANP32E [Acidic (leucine-rich) Nuclear phosphoprotein 32 family, member E] also referred to as LANP-L, LANPL or MGC5350 is a histone chaperone located on chromosome 1q22 and is primarily expressed in human peripheral blood leukocytes, colon, small intestine, prostate, thymus, spleen, skeletal muscle, liver and kidney. It facilitates the genome-wide removal of histone H2A.Z/H2AFZ from the nucleosome. It also blocks the activity of protein phosphatase 2A (PP2A) but not the protein phosphatase 1. Additionally, it may play a pivotal role in cerebellar development and synaptogenesis.

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Synthetic peptide located within the following region: EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDE

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