AV46349
Anti-ANP32E antibody produced in rabbit
affinity isolated antibody
别名:
Anti-Acidic (leucine-rich) Nuclear phosphoprotein 32 family, member E, Anti-LANP-L, Anti-LANPL, Anti-MGC5350
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
31 kDa
种属反应性
bovine, horse, rabbit, human, dog, rat
浓度
0.5 mg - 1 mg/mL
技术
immunohistochemistry: suitable
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... ANP32E(81611)
免疫原
Synthetic peptide directed towards the middle region of human ANP32E
应用
Anti-ANP32E antibody produced in rabbit is suitable for western blotting at a concentration of 0.25μg/ml. It is also useful for immunohistochemistry at a concentration of 4-8μg/ml.
生化/生理作用
ANP32E [Acidic (leucine-rich) Nuclear phosphoprotein 32 family, member E] also referred to as LANP-L, LANPL or MGC5350 is a histone chaperone located on chromosome 1q22 and is primarily expressed in human peripheral blood leukocytes, colon, small intestine, prostate, thymus, spleen, skeletal muscle, liver and kidney. It facilitates the genome-wide removal of histone H2A.Z/H2AFZ from the nucleosome. It also blocks the activity of protein phosphatase 2A (PP2A) but not the protein phosphatase 1. Additionally, it may play a pivotal role in cerebellar development and synaptogenesis.
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
其他说明
Synthetic peptide located within the following region: EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDE
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
未找到合适的产品？
试试我们的产品选型工具.
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
此项目有
M Jiang et al.
Cytogenetic and genome research, 97(1-2), 68-71 (2002-11-20)
Leucine-rich acidic nuclear protein (LANP) is a member of the leucine-rich repeats (LRRs) superfamily. Here we report on a human homologue of LANP, encoded by the gene ANP32E (alias LANPL). The gene was cloned and identified during large-scale sequencing analysis
Arnaud Obri et al.
Nature, 505(7485), 648-653 (2014-01-28)
H2A.Z is an essential histone variant implicated in the regulation of key nuclear events. However, the metazoan chaperones responsible for H2A.Z deposition and its removal from chromatin remain unknown. Here we report the identification and characterization of the human protein
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持