AV48346
Anti-GADD45B antibody produced in rabbit
affinity isolated antibody
别名:
Anti-DKFZP566B133, Anti-GADD45BETA, Anti-Growth arrest and DNA-damage-inducible, β, Anti-MYD118
生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
lyophilized powder
分子量
18 kDa
种属反应性
guinea pig, human, bovine, mouse, horse, canine, rat
浓度
0.5 mg - 1 mg/mL
技术
western blot: suitable
NCBI登记号
UniProt登记号
储存温度
−20°C
基因信息
human ... GADD45B(4616)
一般描述
Growth arrest and DNA-damage-inducible, β (GADD45B) regulates DNA demethylation, adult neurogenesis, p38 signaling and cellular apoptosis. Genetic defects or lack of GADD45B are known to affect long-term memory and synaptic plasticity.
Rabbit Anti-GADD45B antibody recognizes bovine, human, mouse, rat, and canine GADD45B.
Rabbit Anti-GADD45B antibody recognizes bovine, human, mouse, rat, and canine GADD45B.
免疫原
The immunogen for anti-GADD45B antibody: synthetic peptide derected towards the middle region of human GADD45B
应用
Rabbit Anti-GADD45B antibody is suitable for western blot applications at a concentration of 0.25 μg/ml.
外形
Lyophilized from PBS buffer with 2% sucrose
其他说明
Synthetic peptide located within the following region: FCCDNDINIVRVSGMQRLAQLLGEPAETQGTTEARDLHCLLVTNPHTDAW
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
此项目有
Dengke K Ma et al.
Science (New York, N.Y.), 323(5917), 1074-1077 (2009-01-03)
The mammalian brain exhibits diverse types of neural plasticity, including activity-dependent neurogenesis in the adult hippocampus. How transient activation of mature neurons leads to long-lasting modulation of adult neurogenesis is unknown. Here we identify Gadd45b as a neural activity-induced immediate
Da-Liang Ou et al.
Cancer research, 70(22), 9309-9318 (2010-11-11)
Markers that could accurately predict responses to the general kinase inhibitor sorafenib are needed to better leverage its clinical applications. In this study, we examined a hypothesized role in the drug response for the growth arrest DNA damage-inducible gene 45β
Faraz A Sultan et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(48), 17059-17066 (2012-12-01)
Dynamic epigenetic mechanisms including histone and DNA modifications regulate animal behavior and memory. While numerous enzymes regulating these mechanisms have been linked to memory formation, the regulation of active DNA demethylation (i.e., cytosine-5 demethylation) has only recently been investigated. New
Xinheng Zhang et al.
Oncotarget, 7(42), 68883-68893 (2016-09-23)
Avian leukosis virus subgroup J (ALV-J) is a retroviruses that induces neoplasia, hepatomegaly, immunosuppression and poor performance in chickens. The tumorigenic and pathogenic mechanisms of ALV-J remain a hot topic. To explore anti-tumor genes that promote resistance to ALV-J infection
Prescott T Leach et al.
Learning & memory (Cold Spring Harbor, N.Y.), 19(8), 319-324 (2012-07-18)
Growth arrest and DNA damage-inducible β (Gadd45b) has been shown to be involved in DNA demethylation and may be important for cognitive processes. Gadd45b is abnormally expressed in subjects with autism and psychosis, two disorders associated with cognitive deficits. Furthermore
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