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Merck
CN

AV50222

Anti-GALNT13 antibody produced in rabbit

affinity isolated antibody

别名:

Anti-FLJ16031, Anti-FLJ41157, Anti-GalNAc-T13, Anti-H_NH0187G20.1, Anti-KIAA1918, Anti-MGC119459, Anti-MGC119461

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
3
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

64 kDa

species reactivity

mouse, rabbit, dog, horse, bovine, rat, human

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Quality Level

Gene Information

human ... GALNT13(114805)

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General description

GALNT13 is particularly expressed in fetal brain, adult cerebellum, cerebral cortex and whole brain. GALNT13 transcripts are exclusively present in neuroblastoma cells.

Immunogen

Synthetic peptide directed towards the N terminal region of human GALNT13

Application

Anti-GALNT13 antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.

Biochem/physiol Actions

GALNT13 (Polypeptide N-acetylgalactosaminyltransferase 13) catalyzes the O-linked glycosylation of mucins by transfer of N-acetylgalactosamine (GalNAc) with an α-linkage to a serine or threonine residue in protein. It may act as a molecular marker for bone marrow dissemination in human neuroblastoma. GALNT13 is linked to sickle cell disease-associated increased tricuspid regurgitation jet velocity.

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: CNKCDDKKERSLLPALRAVISRNQEGPGEMGKAVLIPKDDQEKMKELFKI

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Nora Berois et al.
Clinical chemistry, 52(9), 1701-1712 (2006-07-29)
To identify new molecular markers of bone marrow dissemination in human neuroblastoma (NB), we studied the transcriptome profiles of malignant neuroblasts established from the human MYCN-amplified IGR-N-91 model. This experimental model includes human neuroblastoma cells derived from a subcutaneous stage
Ankit A Desai et al.
American journal of respiratory and critical care medicine, 186(4), 359-368 (2012-06-09)
An increased tricuspid regurgitation jet velocity (TRV > 2.5 m/s) and pulmonary hypertension defined by right heart catheterization both independently confer increased mortality in sickle cell disease (SCD). We explored the usefulness of peripheral blood mononuclear cell-derived gene signatures as
Yan Zhang et al.
The Journal of biological chemistry, 278(1), 573-584 (2002-10-31)
To date, 10 members of the UDP-N-acetyl-alpha-d-galactosamine:polypeptide N-acetylgalactosaminyltransferase (pp-GalNAc-T) family have been cloned and analyzed in human. In this study, we cloned and analyzed a novel human pp-GalNAc-T from an NT2 cell cDNA library, and we named it pp-GalNAc-T13. In

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