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Merck
CN

B016

Benoxathian hydrochloride

solid

别名:

2-[[[2-(2,6-Dimethoxyphenoxy)ethyl]-amino]-methyl]-1,4-benzoxathian hydrochloride

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关于此项目

经验公式(希尔记法):
C19H23NO4S · HCl
化学文摘社编号:
分子量:
397.92
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
Form:
solid
Quality level:
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form

solid

Quality Level

color

white

solubility

H2O: soluble (Aqueous solutions may be stored for several weeks at -20 °C.), ethanol: soluble, isopropanol: soluble

SMILES string

Cl.COc1cccc(OC)c1OCCNCC2CSc3ccccc3O2

InChI

1S/C19H23NO4S.ClH/c1-21-16-7-5-8-17(22-2)19(16)23-11-10-20-12-14-13-25-18-9-4-3-6-15(18)24-14;/h3-9,14,20H,10-13H2,1-2H3;1H

InChI key

OWRADFDDJVNMGL-UHFFFAOYSA-N

Gene Information

Biochem/physiol Actions

Selective α1-adrenoceptor antagonist.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M A Noguera et al.
British journal of pharmacology, 119(1), 158-164 (1996-09-01)
1. In the present study, depletion of internal Ca2+ stores sensitive to noradrenaline (1 microM) in rat aorta, is the signal for the entry of extracellular Ca2+, not only to refill the stores but also, in our experimental conditions, to
M B Hussain et al.
British journal of pharmacology, 122(5), 849-858 (1998-02-12)
1. The subtype of alpha1-adrenoceptor mediating contractions to phenylephrine of the rat thoracic aorta, mesenteric artery and pulmonary artery were investigated by use of antagonists which show selectivity between the cloned alpha1-adrenoceptor subtypes in binding studies. 2. Cumulative concentration-contraction curves
C H Brown et al.
The Journal of physiology, 507 ( Pt 3), 831-842 (1998-05-23)
1. We have tested the hypothesis that morphine withdrawal excitation of oxytocin neurones that follows from administration of naloxone to morphine-dependent rats is a consequence of excitation of noradrenergic neurones. 2. Female rats were made morphine dependent by intracerebroventricular (i.c.v.)



全球贸易项目编号

货号GTIN
B016-25MG04061832088792
B016-10MG04061832088785