B016
Benoxathian hydrochloride
solid
别名:
2-[[[2-(2,6-Dimethoxyphenoxy)ethyl]-amino]-methyl]-1,4-benzoxathian hydrochloride
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关于此项目
经验公式（希尔记法）:
C19H23NO4S · HCl
化学文摘社编号:
分子量:
397.92
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.77
表单
solid
颜色
white
溶解性
H2O: soluble (Aqueous solutions may be stored for several weeks at -20 °C.)
ethanol: soluble
isopropanol: soluble
SMILES字符串
Cl.COc1cccc(OC)c1OCCNCC2CSc3ccccc3O2
InChI
1S/C19H23NO4S.ClH/c1-21-16-7-5-8-17(22-2)19(16)23-11-10-20-12-14-13-25-18-9-4-3-6-15(18)24-14;/h3-9,14,20H,10-13H2,1-2H3;1H
InChI key
OWRADFDDJVNMGL-UHFFFAOYSA-N
基因信息
human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)
生化/生理作用
Selective α1-adrenoceptor antagonist.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Adrenoceptors in normal and malignant human melanocytes.
A C Scarparo et al.
Archives of dermatological research, 292(5), 265-267 (2000-06-27)
Marie-Christine Pardon et al.
Brain research, 971(1), 55-65 (2003-04-15)
Many psychiatric disorders, including depression, post-traumatic stress disorder and other anxiety disorders, result from an interaction between genetic factors and exposure to a sufficiently sensitizing environmental stressor. The inbred Wistar Kyoto (WKY) rat strain has been proposed as a model
G J Marek et al.
European journal of pharmacology, 305(1-3), 95-100 (1996-06-03)
Pharmacological techniques have defined the existence of two different alpha 1-adrenoceptors, the alpha 1A- and alpha 1B-adrenoceptor subtypes and both of these receptors have been cloned in addition to a cloned alpha 1d-adrenoceptor. A subpopulation of interneurons in layer III
Cauveh Erami et al.
American journal of physiology. Heart and circulatory physiology, 283(4), H1577-H1587 (2002-09-18)
Previous studies suggesting that norepinephrine is directly trophic for the vascular wall have been confounded by concomitant hemodynamic disturbances. Herein, a microcatheter connected to an osmotic minipump was implanted adjacent to the rat carotid for 2-wk perivascular suffusion of agents
A J Douglas et al.
Journal of neuroendocrinology, 17(1), 40-48 (2005-02-22)
We investigated whether changes in noradrenaline neurotransmission in the hypothalamus could explain the hyporesponsiveness of the hypothalamic-pituitary-adrenal (HPA) axis in late pregnancy. Noradrenaline release within the hypothalamic paraventricular nucleus in response to swim stress, as estimated by microdialysis and high-performance
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