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化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Specific activity:
15-65 units/mg protein
Biological source:
fungus (Myrothecium verrucaria)
biological source
fungus (Myrothecium verrucaria)
form
lyophilized powder
specific activity
15-65 units/mg protein
composition
Protein, ≥15% biuret
storage condition
(Keep container tightly closed in a dry and well-ventilated place.)
greener alternative product characteristics
Waste Prevention
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
technique(s)
toxicology assay: suitable
greener alternative category
, Enabling
shipped in
dry ice
storage temp.
−20°C
Quality Level
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General description
我们致力于为您带来更加绿色的替代产品,这些产品遵守一项或多项绿色化学12项原则。对于生物燃料电池研究,本品已根据提高能效和防止废物原则进行了改进。详情参阅《biofiles》文章。
胆红素氧化酶(BOD)属于多铜氧化酶家族亚类成员,常见于真菌。胆红素氧化酶由三个杯状(Cupredoxin-like)结构域组成,含有4个铜离子组成的2个活性位点。研究领域:细胞凋亡
胆红素氧化酶(BOD)属于多铜氧化酶家族亚类成员,常见于真菌。胆红素氧化酶由三个杯状(Cupredoxin-like)结构域组成,含有4个铜离子组成的2个活性位点。研究领域:细胞凋亡
Application
胆红素氧化酶用于降解胆红素。胆红素氧化酶可用于测定黄疸标本中的游离血红蛋白 。在染料流出液脱色方面也有潜在的应用,是治疗新生儿黄疸的潜在药物 。
胆红素氧化酶(来自疣孢漆斑菌)已用于消除胆红素干扰。它还可用于通过荧光素衍生物(FS)标记和多元校正进行直接胆红素(dBR)和总胆红素(tBR)分析。
Biochem/physiol Actions
胆红素氧化酶 (BOD) 是一种催化胆红素氧化为胆绿素的多铜氧化酶。氧是电子受体,被还原成水。在血清的医学检查中,该酶用于血清中胆红素的诊断分析。它也被用作中性条件下工作的生物燃料电池阴极的酶催化剂。是一种单体蛋白,分子量为 60 kDa,在中性 pH 下具有高反应性。BOD 参与卟啉和叶绿素代谢。
胆红素氧化酶(BOD)可氧化漆酶底物。
Other Notes
在 37°C、pH 8.4 时,1 个单位每分钟将氧化 1.0 μmol 的胆红素。
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
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Bilirubin oxidase activity of Bacillus subtilis CotA
Sakasegawa S, et al.
Applied and Environmental Microbiology, 72(1), 972-975 (2006)
James A Cracknell et al.
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The blue multi-copper oxidase bilirubin oxidase (BOx) from the ascomycete plant pathogen Myrothecium verrucaria (Mv) efficiently catalyses the oxidation of bilirubin to biliverdin, with the concomitant reduction of O(2) to water, a reaction of considerable interest for low-temperature bio-fuel cell
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Unlike any protein studied so far, the active site of bilirubin oxidase from Myrothecium verrucaria contains a unique type of covalent link between tryptophan and histidine side chains. The role of this post-translational modification in substrate binding and oxidation is
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