B0390
胆红素氧化酶 来源于疣孢漆斑菌
lyophilized powder, 15-65 units/mg protein
别名:
MvBOx, 胆红素：氧氧化还原酶
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关于此项目
化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Specific activity:
15-65 units/mg protein
Biological source:
fungus (Myrothecium verrucaria)
产品名称
胆红素氧化酶 来源于疣孢漆斑菌, lyophilized powder, 15-65 units/mg protein
biological source
fungus (Myrothecium verrucaria)
form
lyophilized powder
specific activity
15-65 units/mg protein
composition
Protein, ≥15% biuret
storage condition
(Keep container tightly closed in a dry and well-ventilated place.)
greener alternative product characteristics
Waste Prevention
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
technique(s)
toxicology assay: suitable
greener alternative category
, Enabling
shipped in
dry ice
storage temp.
−20°C
Quality Level
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相关类别
Application
胆红素氧化酶用于降解胆红素。胆红素氧化酶可用于测定黄疸标本中的游离血红蛋白 。在染料流出液脱色方面也有潜在的应用，是治疗新生儿黄疸的潜在药物 。
胆红素氧化酶（来自疣孢漆斑菌）已用于消除胆红素干扰。它还可用于通过荧光素衍生物(FS)标记和多元校正进行直接胆红素(dBR)和总胆红素(tBR)分析。
Biochem/physiol Actions
胆红素氧化酶 (BOD) 是一种催化胆红素氧化为胆绿素的多铜氧化酶。氧是电子受体，被还原成水。在血清的医学检查中，该酶用于血清中胆红素的诊断分析。它也被用作中性条件下工作的生物燃料电池阴极的酶催化剂。是一种单体蛋白，分子量为 60 kDa，在中性 pH 下具有高反应性。BOD 参与卟啉和叶绿素代谢。
胆红素氧化酶(BOD)可氧化漆酶底物。
General description
我们致力于为您带来更加绿色的替代产品，这些产品遵守一项或多项绿色化学12项原则。对于生物燃料电池研究，本品已根据提高能效和防止废物原则进行了改进。详情参阅《biofiles》文章。
胆红素氧化酶(BOD)属于多铜氧化酶家族亚类成员，常见于真菌。胆红素氧化酶由三个杯状(Cupredoxin-like)结构域组成，含有4个铜离子组成的2个活性位点。研究领域：细胞凋亡
胆红素氧化酶(BOD)属于多铜氧化酶家族亚类成员，常见于真菌。胆红素氧化酶由三个杯状(Cupredoxin-like)结构域组成，含有4个铜离子组成的2个活性位点。研究领域：细胞凋亡
Other Notes
在 37°C、pH 8.4 时，1 个单位每分钟将氧化 1.0 μmol 的胆红素。
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
Luciano Dos Santos et al.
Physical chemistry chemical physics : PCCP, 12(42), 13962-13974 (2010-09-21)
The 'blue copper' enzyme bilirubin oxidase from Myrothecium verrucaria shows significantly enhanced adsorption on a pyrolytic graphite 'edge' (PGE) electrode that has been covalently modified with naphthyl-2-carboxylate functionalities by diazonium coupling. Modified electrodes coated with bilirubin oxidase show electrocatalytic voltammograms
A'edah Abu-Bakar et al.
Toxicology and applied pharmacology, 257(1), 14-22 (2011-08-30)
We have previously shown that bilirubin (BR), a breakdown product of haem, is a strong inhibitor and a high affinity substrate of the mouse cytochrome P450 2A5 (CYP2A5). The antioxidant BR, which is cytotoxic at high concentrations, is potentially useful
Kimihiko Mizutani et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 66(Pt 7), 765-770 (2010-07-08)
Bilirubin oxidase (BOD), a multicopper oxidase found in Myrothecium verrucaria, catalyzes the oxidation of bilirubin to biliverdin. Oxygen is the electron acceptor and is reduced to water. BOD is used for diagnostic analysis of bilirubin in serum and has attracted
Study of a fluorometric-enzymatic method for bilirubin based on chemically modified bilirubin-oxidase and multivariate calibration
Andreu Y, et al.
Talanta, 57(2), 343-353 (2002)
Franziska Wegerich et al.
Langmuir : the ACS journal of surfaces and colloids, 27(7), 4202-4211 (2011-03-16)
Here, we report on cytochrome c/bilirubin oxidase multilayer electrodes with different cytochrome c (cyt c) forms including mutant forms of human cyt c, which exhibit different reaction rates with bilirubin oxidase (BOD) in solution. The multilayer formation via the layer-by-layer
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