B0436
Anti-BAF57 antibody produced in rabbit
~1 mg/mL, affinity isolated antibody, buffered aqueous solution
别名:
Anti-Mammalian Chromatin Remodeling Complex BRG1-associated Factor 57, Anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 57 kDa
species reactivity
human, mouse
concentration
~1 mg/mL
technique(s)
indirect immunofluorescence: 5-10 μg/mL using mouse NIH-3T3 cells fixed with paraformaldehyde-triton, microarray: suitable, western blot: 0.25-0.5 μg/mL using HeLa nuclear cell extracts
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... SMARCE1(6605)
mouse ... Smarce1(57376)
Immunogen
synthetic peptide corresponding to amino acids 394-411 of human BAF57. The sequence is conserved in mouse.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.
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Jorge Castillo-Robles et al.
Scientific reports, 8(1), 15369-15369 (2018-10-20)
SWI/SNF or BAF chromatin-remodeling complexes are polymorphic assemblies of homologous subunit families that remodel nucleosomes and facilitate tissue-specific gene regulation during development. BAF57/SMARCE1 is a BAF complex subunit encoded in animals by a single gene and is a component of
Oleg Osipovich et al.
Nature immunology, 8(8), 809-816 (2007-06-26)
The assembly of genes encoding antigen receptors is regulated by developmental changes in chromatin that either permit or deny access to a single variable-(diversity)-joining recombinase. These changes are guided by transcriptional promoters and enhancers, which serve as accessibility-control elements in
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