B0436
Anti-BAF57 antibody produced in rabbit
~1 mg/mL, affinity isolated antibody, buffered aqueous solution
别名:
Anti-Mammalian Chromatin Remodeling Complex BRG1-associated Factor 57, Anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1
生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 57 kDa
种属反应性
human, mouse
浓度
~1 mg/mL
技术
indirect immunofluorescence: 5-10 μg/mL using mouse NIH-3T3 cells fixed with paraformaldehyde-triton
microarray: suitable
western blot: 0.25-0.5 μg/mL using HeLa nuclear cell extracts
UniProt登记号
运输
dry ice
储存温度
−20°C
基因信息
human ... SMARCE1(6605)
mouse ... Smarce1(57376)
免疫原
synthetic peptide corresponding to amino acids 394-411 of human BAF57. The sequence is conserved in mouse.
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.
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Jorge Castillo-Robles et al.
Scientific reports, 8(1), 15369-15369 (2018-10-20)
SWI/SNF or BAF chromatin-remodeling complexes are polymorphic assemblies of homologous subunit families that remodel nucleosomes and facilitate tissue-specific gene regulation during development. BAF57/SMARCE1 is a BAF complex subunit encoded in animals by a single gene and is a component of
Oleg Osipovich et al.
Nature immunology, 8(8), 809-816 (2007-06-26)
The assembly of genes encoding antigen receptors is regulated by developmental changes in chromatin that either permit or deny access to a single variable-(diversity)-joining recombinase. These changes are guided by transcriptional promoters and enhancers, which serve as accessibility-control elements in
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