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B0515

倍他米松 17-戊酸酯

Name: 倍他米松 17-戊酸酯
Brand: SIGMA

别名:

9α-氟-16β-甲基-11β,17α,21-三羟基-1,4-孕甾二烯-3,20-二酮 17-戊酸盐, 9α-氟-16β-甲基氢化泼尼松 17-戊酸盐, 倍他米松戊酸盐, 倍他米松戊酸酯

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关于此项目

经验公式（希尔记法）:

C₂₇H₃₇FO₆

化学文摘社编号:

2152-44-5

分子量:

476.58

UNSPSC Code:

12352200

NACRES:

NA.77

PubChem Substance ID:

24891523

MDL number:

MFCD00867446

Beilstein/REAXYS Number:

4240001

Form:

powder

Quality level:

200

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属性

form

powder

Quality Level

200

originator

Schering Plough

storage temp.

2-8°C

SMILES string

CCCCC(=O)O[C@@]1([C@@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)CO

InChI

1S/C27H37FO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17,3)26(19,28)21(31)14-25(20,27)4/h10-11,13,16,19-21,29,31H,5-9,12,14-15H2,1-4H3/t16-,19?,20?,21-,24-,25-,26-,27-/m0/s1

InChI key

SNHRLVCMMWUAJD-QDHNOTTGSA-N

说明

Biochem/physiol Actions

Betamethasone 17-valerate is a synthetic glucocorticoid. It exhibitstherapeutic effects against various allergic and inflammatory skin diseases. Betamethasone 17-valerate also possesses anti-inflammatory properties.

Features and Benefits

This compound was developed by Schering Plough. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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pictograms

GHS08

signalword

Danger

hcodes

H360FD,H373

pcodes

P202 - P260 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 1B - STOT RE 2

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

ppe

Eyeshields, Gloves, type N95 (US)

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Effect of five anti-inflammatory steroids on collagen and glycoaminoglycan synthessis in vitro

Saarni H, et al.

British Journal of Dermatology, 103(2), 167-173 (1980)

Differential suppression of epidermal antimicrobial protein expression in atopic dermatitis and in EFAD mice by pimecrolimus compared to corticosteroids.

Jens-Michael Jensen et al.

Experimental dermatology, 20(10), 783-788 (2011-06-29)

It has been suggested that the increased rate of bacterial infection in atopic dermatitis (AD) may be caused by reduced antimicrobial protein (AMP) expression. We were interested whether common treatments in AD affect antimicrobial defense. We investigated the effects of

Photodegradation and stabilization of betamethasone-17 valerate in aqueous/organic solvents and topical formulations.

Saif-ur-Rehman Khattak et al.

AAPS PharmSciTech, 14(1), 177-182 (2012-12-20)

The effects of solvent [acetonitrile, methanol, and acetonitrile/water mixture (20:80, v/v)], buffer concentration (phosphate buffer, pH 7.5), ionic strength and commonly employed adjuvants on the photodegradation of betamethasone-17 valerate in cream and gel formulations have been studied on exposure to UV

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全球贸易项目编号

货号	GTIN
B0515-25MG	04061832847665
B0515-500MG	04061832847672
B0515-100MG	04061833419878