B1267
生物素-马来酰亚胺
≥95% (TLC), powder
别名:
N-生物素基-N′-(6-马来酰亚胺己酰基)酰肼
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关于此项目
经验公式（希尔记法）:
C20H29N5O5S
化学文摘社编号:
分子量:
451.54
MDL编号:
UNSPSC代码:
12352203
PubChem化学物质编号:
NACRES:
NA.46
质量水平
方案
≥95% (TLC)
表单
powder
溶解性
acetic acid: 20 mg/mL
储存温度
2-8°C
SMILES字符串
O=C(CCCCCN1C(=O)C=CC1=O)NNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23
InChI
1S/C20H29N5O5S/c26-15(7-2-1-5-11-25-17(28)9-10-18(25)29)23-24-16(27)8-4-3-6-14-19-13(12-31-14)21-20(30)22-19/h9-10,13-14,19H,1-8,11-12H2,(H,23,26)(H,24,27)(H2,21,22,30)/t13-,14-,19-/m0/s1
InChI key
VAPZWEFPQRDVHR-NJSLBKSFSA-N
一般描述
生物素-马来酰亚胺是一种生物素特异性硫醇试剂，用于通过人工诱导或天然的巯基对不同蛋白进行生物素化。它可用作通用的多功能硫醇特异性探针。生物素-马来酰亚胺也可用于斑点印迹法检测蛋白SH基。
应用
0.01 mg/ml的生物素-马来酰亚胺PBS（含有0.1％吐温20）溶液室温孵育1小时后可用于检测固定化肽上存在的脱保护的半胱氨酸硫醇。
巯基特异性生物素化试剂。 通过有效的硫醚键偶联。 通常用于偶联到内在巯基，如蛋白，而且不会改变伯胺。
免责声明
除非我们的产品目录或产品随附的其他公司文档中另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人或动物。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
K Gregorius et al.
Analytical biochemistry, 299(1), 84-91 (2001-12-01)
The orientation of an immobilized antigen is important for recognition by, e.g., an antibody. When noncovalent passive adsorption is used for immobilization, the number of ways that the antigen can attach to the surface is numerous and control of how
Camilla To Benfield et al.
Life science alliance, 3(1) (2019-12-13)
Host interferon-induced transmembrane proteins (IFITMs) are broad-spectrum antiviral restriction factors. Of these, IFITM3 potently inhibits viruses that enter cells through acidic endosomes, many of which are zoonotic and emerging viruses with bats (order Chiroptera) as their natural hosts. We previously
E A Bayer et al.
Analytical biochemistry, 149(2), 529-536 (1985-09-01)
A biotin-containing, thiol-specific reagent, 3-(N-maleimido-propionyl) biocytin (MPB), was synthesized and used to biotinylate various proteins via native or artificially induced sulfhydryl groups. In combination with appropriate avidin- or streptavidin-conjugated markers (i.e., fluorescent, enzyme-conjugated, electron-dense, etc.), MPB essentially constitutes a universal
Nicolai T Sand et al.
International journal of molecular sciences, 21(7) (2020-04-05)
Early detection and monitoring of cancer progression is key to successful treatment. Therefore, much research is invested in developing technologies, enabling effective and valuable use of non-invasive liquid biopsies. This includes the detection and analysis of circulating tumor cells (CTCs)
Hongfeng Wang et al.
Autophagy, 16(9), 1683-1696 (2019-12-13)
Significant evidences indicate that reactive oxygen species (ROS) can induce macroautophagy/autophagy under both physiological and pathological conditions. Although the relationship between ROS and autophagy regulation has been well studied, the basic mechanism by which ROS affects autophagy and the biological
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