B170
BW373U86 hydrochloride
powder
表单
powder
技术
HPLC: suitable
gas chromatography (GC): suitable
颜色
tan
溶解性
H2O: 4 mg/mL
包装形式
neat
应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
生化/生理作用
Potent, nonpeptide δ-opioid receptor agonist.
法律信息
Sold with the permission of Delta Pharmaceuticals Inc
免责声明
Hygroscopic, store desiccated
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
K J Chang et al.
The Journal of pharmacology and experimental therapeutics, 267(2), 852-857 (1993-11-01)
Four different opioid receptor binding assays and three different isolated tissue studies were used to screen for delta receptor-selective nonpeptidic compounds. (+/-)-4-((alpha-R*)-alpha-((2S*,5R*)-4-Allyl-2,5- dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N,N-diethylbenzamide (BW373U86) was a potent delta receptor-selective ligand in receptor binding assays. The Ki values were 1.8 +/-
S D Comer et al.
The Journal of pharmacology and experimental therapeutics, 267(2), 866-874 (1993-11-01)
Several opioid agonists were evaluated in pigeons trained to discriminate i.m. injections of sterile water from either the mu agonist morphine (5.6 mg/kg), the kappa agonist bremazocine (0.032mg/kg) or (+/-)-4-((alpha-R*)-alpha-((2S*,5R*)-4-allyl-2,5-dimethyl-1- piperazinyl)-3-hydroxybenzyl)-N,N-diethylbenzamide (BW373U86; 0.56 mg/kg). Pigeons were trained to peak one
Ai Hashimoto et al.
Toxicologic pathology, 48(3), 509-523 (2020-01-04)
Macrophages and myofibroblasts are important in fibrogenesis. The cellular characteristics in pancreatic fibrosis remain to be investigated. Pancreatic fibrosis was induced in F344 rats by a single intravenous injection of dibutyltin dichloride. Histopathologically, the induced pancreatic fibrosis was divided into
S R Childers et al.
Molecular pharmacology, 44(4), 827-834 (1993-10-01)
BW373U86 is a potent and highly selective nonpeptidic agonist for delta-opioid receptors. To determine its ability to couple with G protein-linked second messenger systems, this study examined the effects of BW373U86 on the inhibition of adenylyl cyclase and the stimulation
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