B1758
Biocytin hydrochloride
≥98% (TLC), suitable for drug transporter assays
别名:
Nε-Biotinyl-L-lysine
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关于此项目
经验公式（希尔记法）:
C16H28N4O4S · xHCl
化学文摘社编号:
分子量:
372.48 (free base basis)
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26
产品名称
Biocytin hydrochloride, ≥98% (TLC)
质量水平
方案
≥98% (TLC)
表单
powder
技术
drug transporter assay: suitable
颜色
white to off-white
储存温度
−20°C
SMILES字符串
Cl.NC(CCCCNC(=O)CCCCC1SCC2NC(=O)NC12)C(O)=O
InChI
1S/C16H28N4O4S.ClH/c17-10(15(22)23)5-3-4-8-18-13(21)7-2-1-6-12-14-11(9-25-12)19-16(24)20-14;/h10-12,14H,1-9,17H2,(H,18,21)(H,22,23)(H2,19,20,24);1H
InChI key
FMGQMNFQNPUYBS-UHFFFAOYSA-N
应用
- Biotinylated dextran amine and biocytin hydrochloride are useful tracers for the study of retinal projections in the frog.: This paper highlights the application of biocytin hydrochloride in tracing retinal projections in amphibians. The study demonstrates the efficacy of biocytin hydrochloride in neuroanatomical mapping, facilitating research in visual system development and function (Scalia et al., 1997).
生化/生理作用
Biocytin is used as a substrate to study the specificity and kinetics of biotinidase(s), to measure biotinidase deficiency and as a model compound to study various uptake mechanisms of cells and tissues.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Margaret A MacNeil et al.
The Journal of comparative neurology, 506(1), 6-15 (2007-11-09)
The biocytin wide-field bipolar cell in rabbit retina has a broad axonal arbor in layer 5 of the inner plexiform layer and a wide dendritic arbor that does not contact all cones in its dendritic field. The purpose of our
Barry Wolf et al.
Molecular genetics and metabolism, 86(1-2), 44-50 (2005-09-10)
Biotinidases from various species ranging from fungi and insects to human have specific amino acids, and regions that are evolutionarily conserved. These specific amino acids and regions are further supported by their homology to a variety of amidases and nitrilases
Alessandro R Galloni et al.
eLife, 9 (2020-05-29)
Anatomical similarity across the neocortex has led to the common assumption that the circuitry is modular and performs stereotyped computations. Layer 5 pyramidal neurons (L5PNs) in particular are thought to be central to cortical computation because of their extensive arborisation
James Peak et al.
eLife, 9 (2020-11-21)
The posterior dorsomedial striatum (pDMS) is necessary for goal-directed action; however, the role of the direct (dSPN) and indirect (iSPN) spiny projection neurons in the pDMS in such actions remains unclear. In this series of experiments, we examined the role
Barbara Baur et al.
Brain research, 925(2), 111-121 (2002-01-17)
Uptake of biocytin and biotin was investigated in cultured transformed variants of neuronal (NB2a neuroblastoma) and glial (C6 astrocytoma) CNS cells. NB2a cells took up both compounds but biocytin was transported more efficiently than biotin in the nanomolar concentration range.
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