B2938
BEPP monohydrochloride
≥98% (HPLC), PKR activator, powder
别名:
1H-Benzimidazole-1-ethanol, 2,3-dihydro-2-imino-alpha-(phenoxymethyl)-3-(phenylmethyl)- monohydrochloride
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关于此项目
经验公式（希尔记法）:
C23H23N3O2 HCl
化学文摘社编号:
分子量:
409.91
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
BEPP monohydrochloride, ≥98% (HPLC)
Quality Level
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to off-white
solubility
DMSO: >10 mg/mL
storage temp.
2-8°C
SMILES string
Cl.OC(COc1ccccc1)CN2C(=N)N(Cc3ccccc3)c4ccccc24
InChI
1S/C23H23N3O2.ClH/c24-23-25(15-18-9-3-1-4-10-18)21-13-7-8-14-22(21)26(23)16-19(27)17-28-20-11-5-2-6-12-20;/h1-14,19,24,27H,15-17H2;1H
InChI key
KDMXJFUGIDGZQL-UHFFFAOYSA-N
Biochem/physiol Actions
BEPP is a double-strand RNA-dependent protein kinase (PKR) activator. The double-strand RNA (dsRNA)-dependent protein kinase is a ubiquitously expressed serine threonine kinase, inducible by interferon γ. PRK is involved in several curtail cellular regulations including phosphorylation of eIF2α (which leads to inhibition of protein synthesis and eliciting antivirus and antitumor activities), modulating activities of eIF2α, NF-κB, ATF-3, and p53. BEPP also inhibits the growth of a human lung cancer cell line overexpressing PKR.
BEPP is a double-strand RNA-dependent protein kinase (PKR) activator.
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Ana-Belén Blázquez et al.
PLoS neglected tropical diseases, 15(1), e0009072-e0009072 (2021-01-26)
Usutu virus (USUV) is an African mosquito-borne flavivirus closely related to West Nile, Japanese encephalitis, Zika, and dengue viruses. USUV emerged in 1996 in Europe, where quickly spread across the continent causing a considerable number of bird deaths and varied
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| B2938-25MG | 04061832269306 |
| B2938-5MG | 04061833217498 |
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