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B3251

小檗碱 CRM 氯化物形式

Name: 小檗碱 CRM 氯化物形式
Brand: SIGMA

别名:

二氧化二苯, 盐酸小檗碱, 黄连素

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关于此项目

经验公式（希尔记法）:

C₂₀H₁₈ClNO₄

化学文摘社编号:

633-65-8

分子量:

371.81

EC Number:

211-195-9

UNSPSC Code:

12171500

NACRES:

NA.32

PubChem Substance ID:

24891691

MDL number:

MFCD00011939

Colour Index Number:

75160

Beilstein/REAXYS Number:

3836585

Form:

powder

Quality level:

200

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属性

form

powder

Quality Level

200

solubility

methanol: soluble

SMILES string

COC1=C(C=[N+](CCC2=C3C=C4C(OCO4)=C2)C3=C5)C5=CC=C1OC.[Cl-]

InChI

1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1

InChI key

VKJGBAJNNALVAV-UHFFFAOYSA-M

说明

General description

小檗碱氯化物或天然黄18又称5,6-二氢-9,10-二甲氧基苯并（g）-1,3-苯并二氧杂环己烷（5,6-a）喹啉，是一种苄基四异喹啉植物生物碱。小檗碱含有一种季碱，可以小檗碱氯化物的形式在市场上买到。

Application

小檗碱氯化物是一种荧光染色剂，用于染色肥大细胞中的肝素。小檗碱可上调肝癌细胞中Pgp的表达。

肥大细胞中肝素的荧光染色

Biochem/physiol Actions

一种抗生素特性较弱的生物碱。MDR外排泵的底物。小檗碱的抗微生物活性可通过MDR抑制剂5'-甲氧基氢化物（5'-MHC）加强。小檗碱可上调肝癌细胞中Pgp的表达。用小檗碱进行治疗可能会减少化学治疗药物的积累。

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000503317

0000482257

0000460222

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货号	GTIN
B3251-10G	04061833427439
B3251-25G	04061833427446
B3251-5G	04061833427453