B3251
小檗碱 CRM 氯化物形式
别名:
二氧化二苯, 盐酸小檗碱, 黄连素
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关于此项目
经验公式（希尔记法）:
C20H18ClNO4
化学文摘社编号:
分子量:
371.81
颜色索引号:
75160
Beilstein:
3836585
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.32
表单
powder
溶解性
methanol: soluble
SMILES字符串
COC1=C(C=[N+](CCC2=C3C=C4C(OCO4)=C2)C3=C5)C5=CC=C1OC.[Cl-]
InChI
1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
InChI key
VKJGBAJNNALVAV-UHFFFAOYSA-M
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一般描述
小檗碱氯化物或天然黄18又称5,6-二氢-9,10-二甲氧基苯并（g）-1,3-苯并二氧杂环己烷（5,6-a）喹啉，是一种苄基四异喹啉植物生物碱。小檗碱含有一种季碱，可以小檗碱氯化物的形式在市场上买到。
应用
小檗碱氯化物是一种荧光染色剂，用于染色肥大细胞中的肝素。小檗碱可上调肝癌细胞中Pgp的表达。
肥大细胞中肝素的荧光染色
生化/生理作用
一种抗生素特性较弱的生物碱。MDR外排泵的底物。小檗碱的抗微生物活性可通过MDR抑制剂5'-甲氧基氢化物（5'-MHC）加强。小檗碱可上调肝癌细胞中Pgp的表达。用小檗碱进行治疗可能会减少化学治疗药物的积累。
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
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