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安全信息

B3383

Sigma-Aldrich

联苯胺 二盐酸盐

≥99% (titration)

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别名:
4,4′-二氨基联苯 二盐酸盐
经验公式（希尔记法）:
C12H12N2 · 2HCl
CAS号:
531-85-1
分子量:
257.16
Beilstein:
3914846
EC 号:
208-519-6
MDL编号:
MFCD00040389
PubChem化学物质编号:
24891713
NACRES:
NA.25

质量水平

200

检测方案

≥99% (titration)

形式

powder

SMILES string

Cl[H].Cl[H].Nc1ccc(cc1)-c2ccc(N)cc2

InChI

1S/C12H12N2.2ClH/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10;;/h1-8H,13-14H2;2*1H

InChI key

RUAXWVDEYJEWRY-UHFFFAOYSA-N

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应用

联苯胺（4,4′-二氨基联苯）是一种环境遗传毒素，能够提高暴露人群的癌症患病风险。联苯胺可用作联苯胺分析过程中的参考材料。联苯胺可用于研究其遗传毒性机理。

生化/生理作用

实验动物乳腺中的肿瘤引发剂。

警告

可疑致癌剂

警示用语：

Danger

危险声明

H302 - H350 - H410

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

危险化学品

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K C Morton et al.
Carcinogenesis, 2(8), 747-752 (1981-01-01)
To evaluate the role of metabolism in benzidine (BZ) carcinogenesis, BZ and 2 or its metabolites, N,N'-diacetylbenzidine and N-hydroxy-N,N'-diacetylbenzidine (NOHDABZ), were given by i.p. injection to female CD rats twice weekly for 4 weeks beginning at 30 days of age.
Yan Cao et al.
Stem cells and development, 24(22), 2660-2673 (2015-07-17)
Autophagy is required for hematopoietic stem cell multilineage differentiation, but the underlying mechanism is unknown. Using a conditional mouse model and human leukemia cells, we uncovered a mechanistic link between autophagy and hematopoietic stem cell differentiation. Loss of autophagy in
Lydia C A M Bossers et al.
Forensic science international, 210(1-3), 1-11 (2011-06-11)
Fingermarks formed in or by blood often require specific development techniques. This review examines techniques and materials that may be used to enhance and record fingermarks deposited in blood or fingermarks generated by blood-contaminated papillary ridges. A large number of
K Trivedi et al.
Nanotechnology, 20(40), 405204-405204 (2009-09-10)
This study reports fabrication and characterization of nanoscale organic light emitting diodes with reduced charge spreading. Nanoimprint lithography is used to make SU-8 nanochannels with approximately 90 degrees sidewalls into which N'-bis(naphthalen-1-yl)-N,N'-bis(phenyl)benzidine (NPB) and tris-(8-hydroxyquinoline) aluminum (Alq3) are thermally evaporated
Yi Juan Long et al.
Chemical communications (Cambridge, England), 47(43), 11939-11941 (2011-10-07)
Mercury-stimulated peroxidase mimetic activity of gold nanoparticles was presented, with which a sensitive label-free colorimetric method for Hg(2+) was developed.
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