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Merck
CN

B3383

联苯胺 二盐酸盐

≥99% (titration)

别名:

4,4′-二氨基联苯 二盐酸盐

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关于此项目

经验公式(希尔记法):
C12H12N2 · 2HCl
化学文摘社编号:
分子量:
257.16
Beilstein:
3914846
EC 号:
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.25
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质量水平

方案

≥99% (titration)

表单

powder

SMILES字符串

Cl[H].Cl[H].Nc1ccc(cc1)-c2ccc(N)cc2

InChI

1S/C12H12N2.2ClH/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10;;/h1-8H,13-14H2;2*1H

InChI key

RUAXWVDEYJEWRY-UHFFFAOYSA-N

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应用

联苯胺(4,4′-二氨基联苯)是一种环境遗传毒素,能够提高暴露人群的癌症患病风险。联苯胺可用作联苯胺分析过程中的参考材料。联苯胺可用于研究其遗传毒性机理。

生化/生理作用

实验动物乳腺中的肿瘤引发剂。

免责声明

可疑致癌剂

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

危险化学品
此项目有

历史批次信息供参考:

分析证书(COA)

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K C Morton et al.
Carcinogenesis, 2(8), 747-752 (1981-01-01)
To evaluate the role of metabolism in benzidine (BZ) carcinogenesis, BZ and 2 or its metabolites, N,N'-diacetylbenzidine and N-hydroxy-N,N'-diacetylbenzidine (NOHDABZ), were given by i.p. injection to female CD rats twice weekly for 4 weeks beginning at 30 days of age.
Yan Cao et al.
Stem cells and development, 24(22), 2660-2673 (2015-07-17)
Autophagy is required for hematopoietic stem cell multilineage differentiation, but the underlying mechanism is unknown. Using a conditional mouse model and human leukemia cells, we uncovered a mechanistic link between autophagy and hematopoietic stem cell differentiation. Loss of autophagy in
Jung Woo Lee et al.
Chemical communications (Cambridge, England), 48(3), 422-424 (2011-11-15)
We report a facile route to synthesize size tunable Fe(3)O(4) nanoparticles (NPs)-carbon nitride nanotube (CNNT) hybrids. These hybrids showing the water-soluble property are proven to exhibit ultra high peroxidase mimetic activity compared to those of pure NPs, where a colorless
Juliana Piva de Almeida et al.
Forensic science international, 206(1-3), 58-61 (2010-07-21)
Bloodstains often constitute the major physical evidence in crime investigation. Diluted blood invisible to the naked eye can be detected through presumptive tests however such tests can damage samples and prevent further processing such as DNA analysis. In this study
Lydia C A M Bossers et al.
Forensic science international, 210(1-3), 1-11 (2011-06-11)
Fingermarks formed in or by blood often require specific development techniques. This review examines techniques and materials that may be used to enhance and record fingermarks deposited in blood or fingermarks generated by blood-contaminated papillary ridges. A large number of

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Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.

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