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NACRES:
NA.81
UNSPSC Code:
41106514
Biological source:
bovine pulmonary artery (tunica intima and media)
Growth mode:
Adherent
Morphology:
smooth muscle
Relevant disease(s):
cardiovascular diseases
biological source
bovine pulmonary artery (tunica intima and media)
packaging
pkg of 500,000 cells
manufacturer/tradename
Cell Applications, Inc
growth mode
Adherent
karyotype
2n = 60
morphology
smooth muscle
technique(s)
cell culture | mammalian: suitable
relevant disease(s)
cardiovascular diseases
shipped in
dry ice
storage temp.
−196°C
General description
Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.
BPASMC have been used in studies relevant to pulmonary hypertension characterized by hyperproliferation of pulmonary artery smooth muscle cells, the process shown to be mediated by hypoxia-induced expression of Bcl-xl (Suzuki, 2007). Additionally, they were used to elucidate the PKC-α dependent mechanisms of proMMP-2 activation and other signaling events in smooth muscle cells under pro-inflammatory conditions related to cell growth (Chakraborti, 2009; Roy, 2011, 2013; Dey, 2012; Chowdhury, 2013; Shaikh, 2013).
Characterization: positive for smooth muscle cell specific alpha-actin expression.
BPASMC have been used in studies relevant to pulmonary hypertension characterized by hyperproliferation of pulmonary artery smooth muscle cells, the process shown to be mediated by hypoxia-induced expression of Bcl-xl (Suzuki, 2007). Additionally, they were used to elucidate the PKC-α dependent mechanisms of proMMP-2 activation and other signaling events in smooth muscle cells under pro-inflammatory conditions related to cell growth (Chakraborti, 2009; Roy, 2011, 2013; Dey, 2012; Chowdhury, 2013; Shaikh, 2013).
Characterization: positive for smooth muscle cell specific alpha-actin expression.
Application
cell growth, signaling, receptor transactivation and suppression, vascular remodeling
Biochem/physiol Actions
Artery
Preparation Note
- 2nd passage, >500,000 cells in Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO
- Can be cultured at least 16 doublings
Please refer to the BPASMC Culture Protocol.
Other Notes
Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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