B3805
Anti-Bone Morphogenetic Protein 5 antibody produced in goat
affinity isolated antibody, lyophilized powder
别名:
Anti-BMP-5
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunohistochemistry (frozen sections)
neutralization
western blot
neutralization
western blot
Species reactivity:
human
Citations:
3
Technique(s):
immunohistochemistry (frozen sections): 5-15 μg/mL
neutralization: suitable
western blot: 0.1 μg/mL
neutralization: suitable
western blot: 0.1 μg/mL
Uniprot accession no.:
产品名称
Anti-Bone Morphogenetic Protein 5 antibody produced in goat, affinity isolated antibody, lyophilized powder
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
human
technique(s)
immunohistochemistry (frozen sections): 5-15 μg/mL
neutralization: suitable
western blot: 0.1 μg/mL
UniProt accession no.
application(s)
research pathology
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... BMP5(653)
Biochem/physiol Actions
Bone morphogenetic proteins (BMPs) are the members of the TGF-β superfamily and are identified as the critical factors for formation of bone and cartilage. Apart from this BMPs have immune regulatory functions. The cellular effects of BMPs are mediated by a heteromeric complex composed of type I and type II receptors. BMP5 is required for the development and fine tuning of the skeletal morphology.
Immunogen
recombinant human BMP-5, expressed in NSO cells.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
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存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Steven Pregizer et al.
Cytokine & growth factor reviews, 20(5-6), 509-515 (2009-11-11)
Much evidence suggests that "developmental regulator" genes, like those encoding transcription factors and signaling molecules, are typically controlled by many modular, tissue-specific cis-regulatory elements that function during embryogenesis. These elements are often far from gene coding regions and promoters. Bone
Elina V García et al.
Theriogenology, 81(8), 1032-1041 (2014-03-04)
Bone morphogenetic proteins (BMPs) play a crucial role in mammalian reproduction, but little is known about their expression and function in the oviduct, where preimplantation events take place. In the present study, messenger RNA (mRNA) expression of BMPs was examined
Kohei Miyazono et al.
Cytokine & growth factor reviews, 16(3), 251-263 (2005-05-06)
Bone morphogenetic proteins (BMPs), members of the transforming growth factor-beta (TGF-beta) superfamily, bind to two different serine/threonine kinase receptors, and mediate their signals through Smad-dependent and Smad-independent pathways. Receptor regulated-Smad (R-Smad) proteins specific for the BMP pathways interact with various
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