B4261
生物胞素
≥98% (TLC), suitable for drug transporter assays
别名:
Bct, Nε-(+)-生物素基-L-赖氨酸
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关于此项目
经验公式（希尔记法）:
C16H28N4O4S
化学文摘社编号:
分子量:
372.48
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Beilstein/REAXYS Number:
97197
产品名称
生物胞素, ≥98% (TLC)
Quality Level
assay
≥98% (TLC)
form
powder
optical activity
[α]20/D +53°, c = 1.05% in 0.1 M NaOH(lit.)
technique(s)
drug transporter assay: suitable
color
white to off-white
mp
~245 °C (dec.) (lit.)
storage temp.
−20°C
SMILES string
[H][C@]12CS[C@@H](CCCCC(=O)NCCCC[C@H](N)C(O)=O)[C@@]1([H])NC(=O)N2
InChI
1S/C16H28N4O4S/c17-10(15(22)23)5-3-4-8-18-13(21)7-2-1-6-12-14-11(9-25-12)19-16(24)20-14/h10-12,14H,1-9,17H2,(H,18,21)(H,22,23)(H2,19,20,24)/t10-,11-,12-,14-/m0/s1
InChI key
BAQMYDQNMFBZNA-MNXVOIDGSA-N
Application
生物胞素被作为一种底物，研究生物素酶的特应性和动力学，用来检测生物素酶缺乏症，并且作为模型化合物研究细胞和组织的摄入机制。生物胞素用于标记神经元，中棘神经元和视神经。
Biochem/physiol Actions
生物胞素是赖氨酸和生物素加成。它被生物素酶水解，作用于肽链插入生物素或自由生物素。生物胞素可用作辅酶。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Chen Tian
Investigative Ophthalmology & Visual Science, 57(4) (2016)
Rui Tian et al.
Theranostics, 8(3), 735-745 (2018-01-19)
Purpose: Radionuclide therapy directed against tumors that express somatostatin receptors (SSTRs) has proven effective for the treatment of advanced, low- to intermediate-grade neuroendocrine tumors in the clinic. In clinical usage, somatostatin peptide-based analogs, labeled with therapeutic radionuclides, provide an overall
Jeanne T Paz et al.
Nature neuroscience, 16(1), 64-70 (2012-11-13)
Cerebrocortical injuries such as stroke are a major source of disability. Maladaptive consequences can result from post-injury local reorganization of cortical circuits. For example, epilepsy is a common sequela of cortical stroke, but the mechanisms responsible for seizures following cortical
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| B4261-25MG | 04061833429518 |
| B4261-100MG | 04061833429457 |
| B4261-50MG | 04061833429525 |
| B4261-5MG | 04061832415215 |
| B4261-250MG | 04061833429464 |