B4558
BW B70C
>98% (HPLC), solid
别名:
N-[3-[3-4(-Fluorophenoxy)phenyl]-1-methyl-2-propenyl]-N-hydroxyurea
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关于此项目
经验公式（希尔记法）:
C17H17FN2O3
化学文摘社编号:
分子量:
316.33
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Assay:
>98% (HPLC)
Form:
solid
Quality Segment
assay
>98% (HPLC)
form
solid
color
white
solubility
DMSO: soluble 22 mg/mL
storage temp.
2-8°C
SMILES string
CC(\C=C\c1cccc(Oc2ccc(F)cc2)c1)N(O)C(N)=O
InChI
1S/C17H17FN2O3/c1-12(20(22)17(19)21)5-6-13-3-2-4-16(11-13)23-15-9-7-14(18)8-10-15/h2-12,22H,1H3,(H2,19,21)/b6-5+
InChI key
UAIYNMRLUHHRMF-AATRIKPKSA-N
Gene Information
human ... ALOX5AP(241)
Application
BW B70C has been used as a 5-lipoxygenase inhibitor to study its effects on eryptosis in erythrocytes.
Biochem/physiol Actions
BW B70C exhibits anti-inflammatory and anti-tumorigenic activities. It exhibits therapeutic effects against hepatocellular carcinoma. BW B70C plays a role in allergen-induced bronchoconstriction by reducing the allergic airway closure and glycoconjugate secretion.
Selective 5-lipoxygenase inhibitor.
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)