B4560
6-Bnz-cAMP 钠盐
≥98% (HPLC)
别名:
N6-苯甲酰腺苷-3′，5′-环一磷酸 钠盐
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关于此项目
经验公式（希尔记法）:
C17H15N5O7PNa
化学文摘社编号:
分子量:
455.29
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
质量水平
方案
≥98% (HPLC)
表单
powder
包装
vial of 10 μmol
储存条件
desiccated
颜色
white
溶解性
H2O: freely soluble
运输
dry ice
储存温度
−70°C
SMILES字符串
[Na+].O[C@@H]1[C@@H]2OP([O-])(=O)OC[C@H]2O[C@H]1n3cnc4c(NC(=O)c5ccccc5)ncnc34
InChI
1S/C17H16N5O7P.Na/c23-12-13-10(6-27-30(25,26)29-13)28-17(12)22-8-20-11-14(18-7-19-15(11)22)21-16(24)9-4-2-1-3-5-9;/h1-5,7-8,10,12-13,17,23H,6H2,(H,25,26)(H,18,19,21,24);/q;+1/p-1/t10-,12-,13-,17-;/m1./s1
InChI key
SPYGSKQRPXISIB-FKVBDRBCSA-M
相关类别
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
cGMP induces phase shifts of a mammalian circadian pacemaker at night, in antiphase to cAMP effects.
R A Prosser et al.
Proceedings of the National Academy of Sciences of the United States of America, 86(17), 6812-6815 (1989-09-01)
The suprachiasmatic nuclei (SCN) of mammals contain a circadian clock that synchronizes behavioral and physiological rhythms to the daily cycle of light and darkness. We have been probing the biochemical substrates of this endogenous pacemaker by examining the ability of
M T Hincke et al.
Archives of oral biology, 37(2), 85-92 (1992-02-01)
Beta-adrenergic-stimulated parotid secretion is believed to be mediated by activation of the cAMP-dependent protein kinase (PK-A). However, the relative roles of the type I and II PK-A isoenzymes are still unclear. Combinations of site-selective, lipophilic cAMP analogues that synergistically activate
S Ogawa et al.
The American journal of physiology, 262(3 Pt 1), C546-C554 (1992-03-01)
Prolonged exposure to hypoxia, as at high altitude, results in increased vascular permeability that may be ameliorated by administration of glucocorticoids. To understand mechanisms underlying these observations, cultured bovine aortic and pulmonary artery endothelial cells (ECs) were subjected to hypoxia
Natalia V Bogatcheva et al.
Journal of cellular physiology, 226(12), 3132-3146 (2011-02-09)
Sepsis-induced vascular leakage is a major underlying cause of the respiratory dysfunction seen in severe sepsis. Here, we studied the role of MLC phosphorylation in LPS-induced endothelial hyperpermeability and assessed how the changes in phospho-MLC distribution affect LPS-induced barrier dysfunction.
D O Quissell et al.
Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists, 4(3-4), 443-448 (1993-01-01)
A series of cAMP analogs that have different specificities for the two different binding sites on the regulatory subunit of type I and type II cAMP-dependent protein kinase (PKA) were used to determine whether selective activation of type I or
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