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经验公式(希尔记法):
C23H25N5O2 · HCl
化学文摘社编号:
分子量:
439.94
UNSPSC Code:
12352204
NACRES:
NA.32
PubChem Substance ID:
EC Number:
213-015-4
Beilstein/REAXYS Number:
3823291
MDL number:
InChI key
BNGRKDJZQIGWQF-UHFFFAOYSA-N
InChI
1S/C23H25N5O2.ClH/c24-23(25)26-14-6-11-20(28-21(29)17-8-2-1-3-9-17)22(30)27-19-13-12-16-7-4-5-10-18(16)15-19;/h1-5,7-10,12-13,15,20H,6,11,14H2,(H,27,30)(H,28,29)(H4,24,25,26);1H
SMILES string
Cl[H].NC(=N)NCCCC(NC(=O)c1ccccc1)C(=O)Nc2ccc3ccccc3c2
assay
≥98% (TLC)
form
powder
solubility
DMF: 50 mg/mL, clear, colorless to faintly yellow
storage temp.
2-8°C
Quality Level
General description
胰蛋白酶的显色底物。
Application
Nα-苯甲酰基-DL-精氨酸β-萘酰胺盐酸盐在BANA试验中作为底物用于评价Stefin的抑制活性。它也已用作测定胰蛋白酶抑制剂Ki值的底物。
Biochem/physiol Actions
Nα-苯甲酰基-DL-精氨酸-β萘酰胺盐酸盐(BANA)有助于测定组织蛋白酶B和木瓜蛋白酶的活性。BANA测试也有助于确定牙周致病菌的牙周部位数量。由口腔细菌在牙菌斑或舌苔中合成的挥发性硫化物(VSC)的存在可以通过其水解N-苯甲酰基-DL-精氨酸-2-萘酰胺的能力进行比色确认。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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