产品名称
7- 苄氧羰基-4-(三氟甲基)香豆素, ≥99% (HPLC), solid
质量水平
方案
≥99% (HPLC)
表单
solid
储存温度
−20°C
SMILES字符串
FC(F)(F)C1=CC(=O)Oc2cc(OCc3ccccc3)ccc12
InChI
1S/C17H11F3O3/c18-17(19,20)14-9-16(21)23-15-8-12(6-7-13(14)15)22-10-11-4-2-1-3-5-11/h1-9H,10H2
InChI key
WVKLERKKJXUPIK-UHFFFAOYSA-N
基因信息
rat ... Maoa(29253), Maob(25750)
应用
7-Benzyloxy-4-trifluoromethylcoumarin has been used:
- in the SBAD2-3x-AAGLY hepatocyte-like cell (HLC) functional assay to measure the cytochrome P450 3A4 (CYP3A4)-dependent activity
- in O-dealkylation reaction to determine the activity of CYP3A
- to measure the activity of CYP3A-mediated 7-benzyloxy-4-trifluoromethylcoumarin O-debenzylase activity (BFCOD)
生化/生理作用
Metabolized primarily by cytochrome P450 isozymes CYP1A2 and CYP3A4.
法律信息
Supplied by Gentest Corp., U.S. Patent Nos. 6,207,404.
警示用语：
Warning
危险分类
Acute Tox. 4 Oral
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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