B7188
Blonanserin
≥98% (HPLC)
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关于此项目
经验公式（希尔记法）:
C23H30FN3
化学文摘社编号:
分子量:
367.50
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI key
XVGOZDAJGBALKS-UHFFFAOYSA-N
SMILES string
CCN1CCN(CC1)c2cc(-c3ccc(F)cc3)c4CCCCCCc4n2
InChI
1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3
assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
DMSO: ≥10 mg/mL
originator
Dainippon Sumitomo
storage temp.
room temp
Quality Level
Biochem/physiol Actions
Blonanserin is a D2/5-HT2 receptor antagonist; atypical antipsychotic.
Features and Benefits
This compound was developed by Dainippon Sumitomo. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 4
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Yu-Guan Wen et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 903, 46-52 (2012-07-24)
Blonanserin is a novel atypical antipsychotic with highly selective receptor antagonist activity to dopamine D₂ and 5-HT(2A). N-desethyl blonanserin (blonanserin C) is its major active metabolite in human plasma. Herein we report a new highly sensitive, selective, and rapid liquid
Taro Kishi et al.
Journal of psychiatric research, 47(2), 149-154 (2012-11-08)
There is uncertainty about the efficacy and tolerability of blonanserin in schizophrenia. PubMed, the Cochrane Library databases, PsycINFO, and Google Scholar were searched up to September 2012. A systematic review and meta-analysis of individual patient data from randomized, controlled trials
Atsushi Hamuro et al.
Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 10(4), 198-200 (2010-12-17)
The aim of the present study was to determine the efficacy, side-effects and tolerability of blonanserin for treating refractory behavioural psychological symptoms of dementia (BPSD). The present study was a 12-week, prospective, structured clinical trial of blonanserin for the treatment
Blonanserin for the treatment of delirium patients at an emergency medical care center: an open-label study.
Koji Kato et al.
Asian journal of psychiatry, 6(2), 182-183 (2013-03-08)
Improvement in quetiapine-induced hypoglycemia following a switch to blonanserin.
Yutaro Suzuki et al.
Psychiatry and clinical neurosciences, 66(4), 370-371 (2012-05-26)
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