biological source
Concholepas sp. (Concholepas concholepas )
form
buffered aqueous solution
technique(s)
bioconjugation: suitable
storage temp.
2-8°C
Quality Level
Application
Blue Carrier是一种从软体动物智利鲍鱼的血淋巴中分离得到的载氧蛋白。它具有高度的免疫原性,可用作产生小分子抗体的载体蛋白。该方案的一个例子是关于肌胃糜烂素抗体的生产。
血蓝蛋白是用于抗体生产的载体蛋白。在膀胱癌的治疗中,它用于促进半抗原和肽抗体的生产,是癌症疫苗的一中成分。
Biochem/physiol Actions
用于抗体生产的高可溶性载体蛋白
Physical form
100 mg溶于0.5 mL 0.15 M NaCl、0.1 M磷酸钠,pH 7.2
Legal Information
Blue Carrier is a registered trademark of Biosonda S.A.
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
动植物来源生物产品
此项目有
Bruno Moltedo et al.
The Journal of urology, 176(6 Pt 1), 2690-2695 (2006-11-07)
We determined the antitumor properties of a newly available hemocyanin obtained from the Chilean gastropod Concholepas concholepas (Biosonda Corp., Santiago, Chile) in a syngeneic heterotopic mouse bladder carcinoma model. Since keyhole limpet hemocyanin (Pierce, Rockford, Illinois) is used increasingly in
Enhanced structural stability of Concholepas hemocyanin increases its immunogenicity and maintains its non-specific immunostimulatory effects.
Arancibia S., et al.
European Journal of Immunology (2011)
M I Becker et al.
Hybridoma, 17(4), 373-381 (1998-10-28)
This study is the first report of the development of monoclonal antibodies (MAbs) against gizzerosine (GZ), one of the causative agents of black vomit, a serious poultry disease. Balb/c mice were immunized with different GZ conjugates; the most immunogenic conjugate
Harold Oliva et al.
Hybridoma and hybridomics, 21(5), 365-374 (2002-12-10)
We studied the reactivity of mouse monoclonal antibodies (MAbs) against the hemocyanin from the Chilean marine gastropod Concholepas concholepas (CCH). This protein has been successfully used as a carrier to produce antibodies to haptens and peptides. All MAbs (13) belonging
Anaphylaxis caused by hemocyanin contained in shrimp cephalothorax.
Daiana Guillen et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 113(6), 674-675 (2014-10-14)
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