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B8660

BICINE

Name: BICINE
Brand: SIGMA

BioXtra, ≥99% (titration)

别名:

N,N-双(2-羟乙基)甘氨酸

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关于此项目

经验公式（希尔记法）:

C₆H₁₃NO₄

化学文摘社编号:

150-25-4

分子量:

163.17

UNSPSC Code:

12161700

NACRES:

NA.25

PubChem Substance ID:

24892086

EC Number:

205-755-1

Beilstein/REAXYS Number:

1769362

MDL number:

MFCD00004295

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product line

BioXtra

Quality Level

400

assay

≥99% (titration)

form

powder

impurities

≤0.005% Phosphorus (P), ≤0.1% Insoluble matter

ign. residue

≤0.1%

pH

4.0-6.0 (1 M in H₂O)

useful pH range

7.6-9.0

pKa (25 °C)

8.3

solubility

H₂O: 1 M, clear, colorless

anion traces

chloride (Cl^-): ≤0.05%, sulfate (SO₄^2-): ≤0.05%

cation traces

Al: ≤0.0005%, Ca: <0.001%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH₄⁺: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%

absorption

≤0.05 at 260 in H₂O at 1 M, ≤0.05 at 280 in H₂O at 1 M

application(s)

advanced drug delivery
diagnostic assay manufacturing

storage temp.

room temp

SMILES string

OCCN(CCO)CC(O)=O

InChI

1S/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11)

InChI key

FSVCELGFZIQNCK-UHFFFAOYSA-N

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Application

用于低温生化工作的推荐缓冲液。用于制备稳定的血清鸟嘌呤酶测定底物溶液。通过等发色团法，使用葡聚糖凝胶^® ，作为间隔区分离血浆蛋白。

Legal Information

Sephadex is a registered trademark of Cytiva

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The myosin dimer: an intermediate in the self-assembly of the thick filament of vertebrate skeletal muscle.

J S Davis et al.

FEBS letters, 140(2), 293-297 (1982-04-19)

Mechanism of mercury(II) reductase and influence of ligation on the reduction of mercury(II) by a water soluble 1,5-dihydroflavin.

E Gopinath et al.

Proceedings of the National Academy of Sciences of the United States of America, 86(9), 3041-3044 (1989-05-01)

The nature and rate of reduction of Hg2+ to Hg0 by 1,5-dihydro-3,(3-sulfopropyl)lumiflavin (FIH2) in buffered aqueous solutions (pH 4.7) is dependent on the ligation of Hg2+. In the presence of N,N-bis(2-hydroxyethyl)glycine or when ligated to ethylenediaminetetraacetic acid, the reduction is

Impact of ligand protonation on higher-order metal complexation kinetics in aqueous systems.

Raewyn M Town et al.

The journal of physical chemistry. A, 112(12), 2563-2571 (2008-03-04)

The impact of ligand protonation on the complexation kinetics of higher-order complexes is quantitatively described. The theory is formulated on the basis of the usual situation for metal complex formation in aqueous systems in which the exchange of water for

Irradiation inactivation analysis of acetylcholinesterase and the effect of buffer salts.

D Parkinson et al.

Radiation research, 90(2), 252-259 (1982-05-01)

Free-metal ion depletion by "Good's" buffers.

R Nakon et al.

Science (New York, N.Y.), 221(4612), 749-750 (1983-08-19)

Metal-ion affinity (formation) constants were determined for two "Good's" buffers, N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid (TES) and N,N-bis(2-hydroxyethyl)glycine (bicine). The metal chelates formed undergo loss of an internal ligand (alcohol) proton (bicine) and undergo hydrolysis (bicine and TES) and dimerization reactions (TES). Bicine

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全球贸易项目编号

货号	GTIN
B8660-100G	04061833443163
B8660-250G	04061835542956
B8660-1KG	04061833443170
B8660-25G	04061833443187

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