Anti-Brain-derived Neurotrophic Factor antibody produced in chicken

purified, Sf21-derived, recombinant human brain-derived neurotrophic factor.

Brain derived neurotrophic factor (BDNF) belongs to a family of secreted proteins called neurotrophins that includes, nerve growth factor (NGF), neurotrophin-3 (NT3) and NT4/5. BDNF is expressed in the developing and the mature brain. The downstream pathways promoted by BDNF include PI3K, MAPK and JAK/STAT. The most important role of BDNF is the regulation of synaptic transmission and plasticity, protein synthesis and phosphorylation of local proteins.

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

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