B9688
苯噻啶
≥98% (HPLC)
别名:
Pizotifen, Pizotyline; 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine
登录查看公司和协议定价
选择尺寸
关于此项目
经验公式（希尔记法）:
C19H21NS
化学文摘社编号:
分子量:
295.44
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
方案
≥98% (HPLC)
表单
powder
溶解性
DMSO: ≥8 mg/mL
创始人
Novartis
储存温度
room temp
SMILES字符串
CN1CCC(\CC1)=C2\c3ccccc3CCc4sccc24
InChI
1S/C19H21NS/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18/h2-5,10,13H,6-9,11-12H2,1H3
InChI key
FIADGNVRKBPQEU-UHFFFAOYSA-N
生化/生理作用
Pizotifen is a Serotonin antagonist used for prophylaxis of migraine
Pizotifen is a serotonin antagonist acting mainly at the 5-HT1, 5-HT2A and 5HT2C receptors with some antihistamine activity. It is used for the prevention of vascular headache including migraine and cluster headache.
特点和优势
This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Repr. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
M V Margarit et al.
Drug development and industrial pharmacy, 27(6), 517-522 (2001-09-11)
We analyzed the physicochemical characteristics of solid dispersions of pizotifen malate and povidone (Kollidon 12) at different proportions; we used X-ray diffraction, infrared spectrometry and differential scanning calorimetry (DSC) and tested the solubility of the solid dispersions in equilibrium. The
Prophylaxis of migraine headache.
Tamara Pringsheim et al.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 182(7), E269-E276 (2010-02-18)
A Huertas-Ceballos et al.
The Cochrane database of systematic reviews, (1)(1), CD003017-CD003017 (2008-02-07)
Between 4% and 25% of school-age children complain of recurrent abdominal pain (RAP) of sufficient severity to interfere with daily activities. For the majority no organic cause for their pain can be found on physical examination or investigation and although
Rachel Ej Besser et al.
Acta paediatrica (Oslo, Norway : 1992), 94(12), 1860-1862 (2006-01-20)
We report a case of two siblings with Raynaud phenomena and migraine, whose symptoms were successfully treated with pizotifen. To our knowledge, this is the first case documenting the association between Raynaud phenomena and migraine in two siblings with a
Ying Jiang et al.
Experimental and therapeutic medicine, 19(2), 817-824 (2020-02-06)
Gastric cancer is the fifth most common malignancy and the third highest cause of cancer-associated mortality worldwide. Therefore, research on the pathogenesis of gastric cancer is of utmost importance. It has been reported that aberrant activation of the Wnt/β-catenin signaling
商品
We offer many products related to serotonin receptors for your research needs.
我们提供许多血清素受体相关产品，满足您的各类研究需求。
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持