BM0021
BMY-14802
≥97% (HPLC)
别名:
α-(4-Fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol, (±)-BMY 14802, BMS 181100, BMY-014802, BMY14802
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选择尺寸
关于此项目
经验公式（希尔记法）:
C18H22F2N4O
化学文摘社编号:
分子量:
348.39
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
InChI
1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2
SMILES string
FC1=CC=C(C(O)CCCN2CCN(C3=NC=C(F)C=N3)CC2)C=C1
InChI key
ZXUYYZPJUGQHLQ-UHFFFAOYSA-N
assay
≥97% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
room temp
Biochem/physiol Actions
BMY-14802 is a potent and selective sigma-1 (σ1) receptor antagonist with an IC50 value of approximately 100 nM. BMY-14802 shows low affinity at serotonin (5-HT) 1A and adrenergic σ1 receptors and minimal activity at dopamine receptors. BMY-14802 has exhibited antipsychotic activity in rodent models and anti-dyskinetic effects against L-DOPA with preservation of antiparkinsonian efficacy.
BMY-14802 is a potent and selective sigma-1 (σ1) receptor antagonist.
Features and Benefits
BMY-14802 is available through a partnership with Bristol-Myers Squibb (BMS). To learn more and view other BMS compounds, visit sigma.com/BMS.
Legal Information
Sold for research purposes only under agreement from BMS.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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