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Merck
CN

BX-0600-30

Human Cortical Astrocytes

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Human iPSC line, Fully differentiated, Healthy Male Control (no known neurological disorders), Cryopreserved

别名:

Cerebral Astrocytes

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生物来源

human (iPSC line)

表单

frozen liquid

包装

vial of 1 (contains ≥1 million cells)

技术

cell culture | mammalian: suitable

储存温度

-140 to -196°C

一般描述

Human iPSC-Derived Cortical Astrocytes. Required products (sold separately): BX-2600-100uL, BX-2020-100uL. Specialized glia that are the majority of the central nervous system (CNS), astrocytes do not conduct electrical signals but promote the health of the CNS through regulating the blood-brain barrier (BBB), excess neurotransmitter clearance, and maintaining ion balance, and more. Related diseases: Autism, Epilepsy, AD, HD

应用

Function: Cortical Astrocytes uptake glutamate. Improved neurite outgrowth in the presence of astrocytes. Energy and structural support cell for cortical neurons and immune response.

特点和优势

Marker Expression and Morphology: Fully differentiated Cortical Astrocytes express key astrocyte markers GFAP (green) and S100β (red) at >90% and exhibit mature process-bearing morphologies (shown here with a DAPI stain).

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Single-cell analysis reveals inflammatory interactions driving macular degeneration
Manik Kuchroo, Marcello DiStasio , Eric Song, Eda Calapkulu, et.al.
Nature Communications, 1 (2023)

实验方案

Discover an expert protocol for seeding and culturing spiny striatal GABAergic neuron in monoculture. Explore spiny GABAergic neurons and culture reagents.

Discover an expert protocol for culturing cortical glutamatergic neurons in monoculture. Explore glutamatergic neurons culture cells and reagents.

Discover an expert protocol for seeding and culturing astrocytes in monoculture. Explore high purity astrocytes and culture reagents.

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